Relationship between obesity and leptin serum among low socioeconomic primary school children aged 5-7 years

Background Obesity has become a major health problem globally, indicates as an epidemic problem by World Health Organization (WHO). Adiposity rebound period may represent critical period for the development of adiposity. Recent data suggest that, in industrialized countries, people of low socioecono...

Full description

Bibliographic Details
Main Authors: Soenarto Soenarto, Helena Anneke Sendow-Tangkilisan
Format: Article
Language:English
Published: Indonesian Pediatric Society Publishing House 2010-06-01
Series:Paediatrica Indonesiana
Subjects:
Online Access:https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/824
_version_ 1818559976533131264
author Soenarto Soenarto
Helena Anneke Sendow-Tangkilisan
author_facet Soenarto Soenarto
Helena Anneke Sendow-Tangkilisan
author_sort Soenarto Soenarto
collection DOAJ
description Background Obesity has become a major health problem globally, indicates as an epidemic problem by World Health Organization (WHO). Adiposity rebound period may represent critical period for the development of adiposity. Recent data suggest that, in industrialized countries, people of low socioeconomic group are more likely to be obese than their high socioeconomic counterparts. Level of serum leptin was reported to be higher in obese subjects. There has been lack of data regarding leptin serum level in Indonesian obese children. Objective This study aimed to investigate leptin serum level in low socioeconomic obese children.  Methods This was a cross sectional study perfonned in Tuminting District, Manado. Obesity was defined based on body mass index for Asia􀁇Pacific condition, i.e., grade I obesity (BMI 25/29.9 kg/ mL), grade II (BM] 30-40 kg/ml), and grade III (BM] > 40 kg/m2 Low socioeconomic status was detennined based on Government's program Cash Direct Aid Program. loBod sample was obtained from inclusion subjects, consisted of leptin serum. Results Fifty􀁇two low socioeconomic obese children were eligible \\lith age ranged between 5 to 7 years. They were divided into grade ] obesity (43 or 82.7%), and grade II (9 or 17.3%). The lowest leptin blood level was 10,291 pg/mL, while the highest was 41,500 pg/dL. All girls had nonnal serum leptin level; in contrast all boys had increased serum leptin level.  Conclusions Leprin level increased in those subjects whose BMI increased.
first_indexed 2024-12-14T00:32:31Z
format Article
id doaj.art-03d5f78b3ded4d55bdb266ea873c1675
institution Directory Open Access Journal
issn 0030-9311
2338-476X
language English
last_indexed 2024-12-14T00:32:31Z
publishDate 2010-06-01
publisher Indonesian Pediatric Society Publishing House
record_format Article
series Paediatrica Indonesiana
spelling doaj.art-03d5f78b3ded4d55bdb266ea873c16752022-12-21T23:24:46ZengIndonesian Pediatric Society Publishing HousePaediatrica Indonesiana0030-93112338-476X2010-06-01503166910.14238/pi50.3.2010.166-9687Relationship between obesity and leptin serum among low socioeconomic primary school children aged 5-7 yearsSoenarto Soenarto0Helena Anneke Sendow-Tangkilisan1Department of Child Health, Sam Ratulangi University Medical School/Prof. Dr. R.D.Kandou Hospital, ManadoDepartment of Child Health, Sam Ratulangi University Medical School/Prof. Dr. R.D.Kandou Hospital, ManadoBackground Obesity has become a major health problem globally, indicates as an epidemic problem by World Health Organization (WHO). Adiposity rebound period may represent critical period for the development of adiposity. Recent data suggest that, in industrialized countries, people of low socioeconomic group are more likely to be obese than their high socioeconomic counterparts. Level of serum leptin was reported to be higher in obese subjects. There has been lack of data regarding leptin serum level in Indonesian obese children. Objective This study aimed to investigate leptin serum level in low socioeconomic obese children.  Methods This was a cross sectional study perfonned in Tuminting District, Manado. Obesity was defined based on body mass index for Asia􀁇Pacific condition, i.e., grade I obesity (BMI 25/29.9 kg/ mL), grade II (BM] 30-40 kg/ml), and grade III (BM] > 40 kg/m2 Low socioeconomic status was detennined based on Government's program Cash Direct Aid Program. loBod sample was obtained from inclusion subjects, consisted of leptin serum. Results Fifty􀁇two low socioeconomic obese children were eligible \\lith age ranged between 5 to 7 years. They were divided into grade ] obesity (43 or 82.7%), and grade II (9 or 17.3%). The lowest leptin blood level was 10,291 pg/mL, while the highest was 41,500 pg/dL. All girls had nonnal serum leptin level; in contrast all boys had increased serum leptin level.  Conclusions Leprin level increased in those subjects whose BMI increased.https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/824childrenobesitylow socioeconomicleptin
spellingShingle Soenarto Soenarto
Helena Anneke Sendow-Tangkilisan
Relationship between obesity and leptin serum among low socioeconomic primary school children aged 5-7 years
Paediatrica Indonesiana
children
obesity
low socioeconomic
leptin
title Relationship between obesity and leptin serum among low socioeconomic primary school children aged 5-7 years
title_full Relationship between obesity and leptin serum among low socioeconomic primary school children aged 5-7 years
title_fullStr Relationship between obesity and leptin serum among low socioeconomic primary school children aged 5-7 years
title_full_unstemmed Relationship between obesity and leptin serum among low socioeconomic primary school children aged 5-7 years
title_short Relationship between obesity and leptin serum among low socioeconomic primary school children aged 5-7 years
title_sort relationship between obesity and leptin serum among low socioeconomic primary school children aged 5 7 years
topic children
obesity
low socioeconomic
leptin
url https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/824
work_keys_str_mv AT soenartosoenarto relationshipbetweenobesityandleptinserumamonglowsocioeconomicprimaryschoolchildrenaged57years
AT helenaannekesendowtangkilisan relationshipbetweenobesityandleptinserumamonglowsocioeconomicprimaryschoolchildrenaged57years