First-episode mania after COVID-19: A case series in Iran
BackgroundIncreasing reports of manic episodes in patients during acute infection with COVID-19 have been documented since the pandemic began, including individuals without a previous personal or family history of bipolar disorder. As infections and autoimmunity have putative roles in bipolar disord...
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-04-01
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| Series: | Frontiers in Psychiatry |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fpsyt.2023.1102450/full |
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| author | Mahdieh Saeidi Tara Rezvankhah Victor Pereira-Sanchez Maryam Rafieian Behnam Shariati Soode Tajik Esmaeeli Maziar Emamikhah Kaveh Alavi Amir Shabani Shiva Soraya Fatemeh Kashaninasab Fatemeh Sadat Mirfazeli |
| author_facet | Mahdieh Saeidi Tara Rezvankhah Victor Pereira-Sanchez Maryam Rafieian Behnam Shariati Soode Tajik Esmaeeli Maziar Emamikhah Kaveh Alavi Amir Shabani Shiva Soraya Fatemeh Kashaninasab Fatemeh Sadat Mirfazeli |
| author_sort | Mahdieh Saeidi |
| collection | DOAJ |
| description | BackgroundIncreasing reports of manic episodes in patients during acute infection with COVID-19 have been documented since the pandemic began, including individuals without a previous personal or family history of bipolar disorder. As infections and autoimmunity have putative roles in bipolar disorder, we aimed to document the clinical presentations, associated stressors, family aggregation patterns, and brain imaging and electroencephalographic correlates with a series of patients with episodes of mania that emerged shortly after COVID-19 infections.MethodsWe obtained all relevant clinical information from 12 patients whose first manic episode started within a month of COVID-19 infection and were treated at Rasool-e-Akram hospital and Iran psychiatric hospital, two tertiary medical centers in Tehran, Iran, in 2021.ResultsPatients had a mean age of 44. The interval between the onset of symptoms of COVID and mania ranged between 0 and 28 days (mean: 16.25, median: 14 days); it was observed to be shorter in patients with a family history of mood disorders but not in those receiving corticosteroids. Alongside a descriptive overview of our sample, we provide detailed narrative descriptions of two of the cases for illustrative purposes and discuss our observations in the context of other cases reported elsewhere and the state-of-the-art regarding infectious diseases, COVID-19, and bipolar disorder as reported in previous literature.ConclusionOur case series documents observational and naturalistic evidence from a dozen of cases of mania in the context of acute COVID-19, which, while limited, calls for analytical research of the phenomenon, and points at a family history of bipolar disorder and the use of corticosteroids as factors for particular focus. |
| first_indexed | 2024-04-09T18:39:10Z |
| format | Article |
| id | doaj.art-03d6dcfd75d9496b81dcbf34e2a90925 |
| institution | Directory Open Access Journal |
| issn | 1664-0640 |
| language | English |
| last_indexed | 2024-04-09T18:39:10Z |
| publishDate | 2023-04-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Psychiatry |
| spelling | doaj.art-03d6dcfd75d9496b81dcbf34e2a909252023-04-11T06:05:08ZengFrontiers Media S.A.Frontiers in Psychiatry1664-06402023-04-011410.3389/fpsyt.2023.11024501102450First-episode mania after COVID-19: A case series in IranMahdieh Saeidi0Tara Rezvankhah1Victor Pereira-Sanchez2Maryam Rafieian3Behnam Shariati4Soode Tajik Esmaeeli5Maziar Emamikhah6Kaveh Alavi7Amir Shabani8Shiva Soraya9Fatemeh Kashaninasab10Fatemeh Sadat Mirfazeli11Department of Psychiatry, Mental Health Research Center, School of Behavioral Sciences and Mental Health (Tehran Institute of Psychiatry), Iran University of Medical Sciences, Tehran, IranDepartment of Psychiatry, Mental Health Research Center, School of Behavioral Sciences and Mental Health (Tehran Institute of Psychiatry), Iran University of Medical Sciences, Tehran, IranGrossman School of Medicine, New York University, New York, NY, United StatesDepartment of Psychiatry, Mental Health Research Center, School of Behavioral Sciences and Mental Health (Tehran Institute of Psychiatry), Iran University of Medical Sciences, Tehran, IranDepartment of Psychiatry, Mental Health Research Center, School of Behavioral Sciences and Mental Health (Tehran Institute of Psychiatry), Iran University of Medical Sciences, Tehran, IranDepartment of Psychiatry, Mental Health Research Center, School of Behavioral Sciences and Mental Health (Tehran Institute of Psychiatry), Iran University of Medical Sciences, Tehran, IranDepartment of Psychiatry, Mental Health Research Center, School of Behavioral Sciences and Mental Health (Tehran Institute of Psychiatry), Iran University of Medical Sciences, Tehran, IranDepartment of Psychiatry, Mental Health Research Center, School of Behavioral Sciences and Mental Health (Tehran Institute of Psychiatry), Iran University of Medical Sciences, Tehran, IranDepartment of Psychiatry, Mental Health Research Center, School of Behavioral Sciences and Mental Health (Tehran Institute of Psychiatry), Iran University of Medical Sciences, Tehran, IranDepartment of Psychiatry, Mental Health Research Center, School of Behavioral Sciences and Mental Health (Tehran Institute of Psychiatry), Iran University of Medical Sciences, Tehran, IranDepartment of Psychiatry, Mental Health Research Center, School of Behavioral Sciences and Mental Health (Tehran Institute of Psychiatry), Iran University of Medical Sciences, Tehran, IranDepartment of Psychiatry, Mental Health Research Center, School of Behavioral Sciences and Mental Health (Tehran Institute of Psychiatry), Iran University of Medical Sciences, Tehran, IranBackgroundIncreasing reports of manic episodes in patients during acute infection with COVID-19 have been documented since the pandemic began, including individuals without a previous personal or family history of bipolar disorder. As infections and autoimmunity have putative roles in bipolar disorder, we aimed to document the clinical presentations, associated stressors, family aggregation patterns, and brain imaging and electroencephalographic correlates with a series of patients with episodes of mania that emerged shortly after COVID-19 infections.MethodsWe obtained all relevant clinical information from 12 patients whose first manic episode started within a month of COVID-19 infection and were treated at Rasool-e-Akram hospital and Iran psychiatric hospital, two tertiary medical centers in Tehran, Iran, in 2021.ResultsPatients had a mean age of 44. The interval between the onset of symptoms of COVID and mania ranged between 0 and 28 days (mean: 16.25, median: 14 days); it was observed to be shorter in patients with a family history of mood disorders but not in those receiving corticosteroids. Alongside a descriptive overview of our sample, we provide detailed narrative descriptions of two of the cases for illustrative purposes and discuss our observations in the context of other cases reported elsewhere and the state-of-the-art regarding infectious diseases, COVID-19, and bipolar disorder as reported in previous literature.ConclusionOur case series documents observational and naturalistic evidence from a dozen of cases of mania in the context of acute COVID-19, which, while limited, calls for analytical research of the phenomenon, and points at a family history of bipolar disorder and the use of corticosteroids as factors for particular focus.https://www.frontiersin.org/articles/10.3389/fpsyt.2023.1102450/fullCOVID-19maniabipolar disorderpandemicfirst-episode mania |
| spellingShingle | Mahdieh Saeidi Tara Rezvankhah Victor Pereira-Sanchez Maryam Rafieian Behnam Shariati Soode Tajik Esmaeeli Maziar Emamikhah Kaveh Alavi Amir Shabani Shiva Soraya Fatemeh Kashaninasab Fatemeh Sadat Mirfazeli First-episode mania after COVID-19: A case series in Iran Frontiers in Psychiatry COVID-19 mania bipolar disorder pandemic first-episode mania |
| title | First-episode mania after COVID-19: A case series in Iran |
| title_full | First-episode mania after COVID-19: A case series in Iran |
| title_fullStr | First-episode mania after COVID-19: A case series in Iran |
| title_full_unstemmed | First-episode mania after COVID-19: A case series in Iran |
| title_short | First-episode mania after COVID-19: A case series in Iran |
| title_sort | first episode mania after covid 19 a case series in iran |
| topic | COVID-19 mania bipolar disorder pandemic first-episode mania |
| url | https://www.frontiersin.org/articles/10.3389/fpsyt.2023.1102450/full |
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