Modulation of radiation-induced base excision repair pathway gene expression by melatonin

Modulation of radiation-induced base excision repair pathway gene expression by melatonin

Objective: Approximately 70% of all cancer patients receive radiotherapy. Although radiotherapy is effective in killing cancer cells, it has adverse effects on normal cells as well. Melatonin (MLT) as a potent antioxidant and anti-inflammatory agent has been proposed to stimulate DNA repair capacity...

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Bibliographic Details
Main Authors: Saeed Rezapoor, Alireza Shirazi, Sakineh Abbasi, Javad Tavakkoly Bazzaz, Pantea Izadi, Hamed Rezaeejam, Majid Valizadeh, Farid Soleimani-Mohammadi, Masoud Najafi
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2017-01-01
Series:Journal of Medical Physics
Subjects:
Base excision repair
gene expression
melatonin
radiation
real-time-polymerase chain reaction
Online Access:http://www.jmp.org.in/article.asp?issn=0971-6203;year=2017;volume=42;issue=4;spage=245;epage=250;aulast=Rezapoor

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