Nearly 30 Years of Treatment for Recurrent Granulosa Cell Tumor of the Ovary: A Case Report and Review of the Literature
A 30-year-old woman was diagnosed with a stage IA granulosa cell tumor (GCT) of the ovary in 1979. Following removal of the adnexal mass and complete surgical staging, she remained disease-free for 12 years. In 1991 she underwent a resection of a retroperitoneal mass, confirmed to be a recurrent GCT...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Karger Publishers
2010-01-01
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| Series: | Case Reports in Oncology |
| Subjects: | |
| Online Access: | http://www.karger.com/Article/FullText/274590 |
| _version_ | 1819207766777004032 |
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| author | Deanna Teoh Ralph Freedman Pamela T. Soliman |
| author_facet | Deanna Teoh Ralph Freedman Pamela T. Soliman |
| author_sort | Deanna Teoh |
| collection | DOAJ |
| description | A 30-year-old woman was diagnosed with a stage IA granulosa cell tumor (GCT) of the ovary in 1979. Following removal of the adnexal mass and complete surgical staging, she remained disease-free for 12 years. In 1991 she underwent a resection of a retroperitoneal mass, confirmed to be a recurrent GCT. Despite adjuvant radiation treatment at the time of recurrence, the patient presented five years later with abdominal pain, and was found to have a second recurrence. Over the next 10 years the patient had multiple recurrences and progressive disease despite surgical resection, cytotoxic, hormonal and targeted chemotherapy treatments. In conclusion, there is no standard management for recurrent GCT of the ovary. We review this patient’s treatment in the context of the current literature. |
| first_indexed | 2024-12-23T05:28:43Z |
| format | Article |
| id | doaj.art-03d85447627845849a86f2fe872d305c |
| institution | Directory Open Access Journal |
| issn | 1662-6575 |
| language | English |
| last_indexed | 2024-12-23T05:28:43Z |
| publishDate | 2010-01-01 |
| publisher | Karger Publishers |
| record_format | Article |
| series | Case Reports in Oncology |
| spelling | doaj.art-03d85447627845849a86f2fe872d305c2022-12-21T17:58:31ZengKarger PublishersCase Reports in Oncology1662-65752010-01-0131141810.1159/000274590274590Nearly 30 Years of Treatment for Recurrent Granulosa Cell Tumor of the Ovary: A Case Report and Review of the LiteratureDeanna TeohRalph FreedmanPamela T. SolimanA 30-year-old woman was diagnosed with a stage IA granulosa cell tumor (GCT) of the ovary in 1979. Following removal of the adnexal mass and complete surgical staging, she remained disease-free for 12 years. In 1991 she underwent a resection of a retroperitoneal mass, confirmed to be a recurrent GCT. Despite adjuvant radiation treatment at the time of recurrence, the patient presented five years later with abdominal pain, and was found to have a second recurrence. Over the next 10 years the patient had multiple recurrences and progressive disease despite surgical resection, cytotoxic, hormonal and targeted chemotherapy treatments. In conclusion, there is no standard management for recurrent GCT of the ovary. We review this patient’s treatment in the context of the current literature.http://www.karger.com/Article/FullText/274590ChemotherapyOvarian cancerGranulosa cell tumorHormonal therapy |
| spellingShingle | Deanna Teoh Ralph Freedman Pamela T. Soliman Nearly 30 Years of Treatment for Recurrent Granulosa Cell Tumor of the Ovary: A Case Report and Review of the Literature Case Reports in Oncology Chemotherapy Ovarian cancer Granulosa cell tumor Hormonal therapy |
| title | Nearly 30 Years of Treatment for Recurrent Granulosa Cell Tumor of the Ovary: A Case Report and Review of the Literature |
| title_full | Nearly 30 Years of Treatment for Recurrent Granulosa Cell Tumor of the Ovary: A Case Report and Review of the Literature |
| title_fullStr | Nearly 30 Years of Treatment for Recurrent Granulosa Cell Tumor of the Ovary: A Case Report and Review of the Literature |
| title_full_unstemmed | Nearly 30 Years of Treatment for Recurrent Granulosa Cell Tumor of the Ovary: A Case Report and Review of the Literature |
| title_short | Nearly 30 Years of Treatment for Recurrent Granulosa Cell Tumor of the Ovary: A Case Report and Review of the Literature |
| title_sort | nearly 30 years of treatment for recurrent granulosa cell tumor of the ovary a case report and review of the literature |
| topic | Chemotherapy Ovarian cancer Granulosa cell tumor Hormonal therapy |
| url | http://www.karger.com/Article/FullText/274590 |
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