Cardiovascular risk factors affecting COVID-19 outcomes at a tertiary referral hospital in northwest Iran: A prospective cohort study
Objective: To investigate cardiovascular risk factors affecting COVID-19 outcomes in a tertiary referral hospital. Methods: This prospective cohort study analyzed 269 participants with COVID-19. The primary outcomes were ICU admission, prolonged hospital stay duration, and in-hospital death. The sec...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2024-01-01
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| Series: | Journal of Acute Disease |
| Subjects: | |
| Online Access: | http://www.jadweb.org/article.asp?issn=2221-6189;year=2024;volume=13;issue=1;spage=8;epage=13;aulast=Behnemoon |
| _version_ | 1797219157271379968 |
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| author | Mahsa Behnemoon Mojdeh Mehrno Naser Gharebaghi Milad Hamdi |
| author_facet | Mahsa Behnemoon Mojdeh Mehrno Naser Gharebaghi Milad Hamdi |
| author_sort | Mahsa Behnemoon |
| collection | DOAJ |
| description | Objective: To investigate cardiovascular risk factors affecting COVID-19 outcomes in a tertiary referral hospital.
Methods: This prospective cohort study analyzed 269 participants with COVID-19. The primary outcomes were ICU admission, prolonged hospital stay duration, and in-hospital death. The secondary outcomes included death, chronic symptoms, and NYHA functional class during follow-up periods.
Results: A total of 412 patients with COVID-19 symptoms were enrolled in the study, and out of which 269 patients had complete medical records and positive SARS-CoV-2 PCR test results, fulfilling the study criteria were analyzed. The patients were divided into two groups, with cardiovascular comorbidities (group A, n=122), such as established cardiovascular disease, diabetes mellitus, and hypertension, and without cardiovascular comorbidities (group B, n=147). Binary logistic regression analysis showed that patients with underlying hypertension, diabetes, and established cardiovascular disease had a 1.55 (95% CI: 1.28-2.26), 1.62 (95% CI: 1.34-2.13), and 1.63 (95% CI: 1.07-5.34)-fold risk of mortality, respectively in the adjusted model.
Conclusions: Hospitalized COVID-19 patients with predisposing cardiovascular risk factors are more susceptible to develop worse outcomes. More attention should be paid to the management and follow-up of these patients. |
| first_indexed | 2024-04-24T12:29:11Z |
| format | Article |
| id | doaj.art-03dc524e93e4406c8cf0230488f0dde6 |
| institution | Directory Open Access Journal |
| issn | 2221-6189 2589-5516 |
| language | English |
| last_indexed | 2024-04-24T12:29:11Z |
| publishDate | 2024-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Acute Disease |
| spelling | doaj.art-03dc524e93e4406c8cf0230488f0dde62024-04-08T07:32:21ZengWolters Kluwer Medknow PublicationsJournal of Acute Disease2221-61892589-55162024-01-0113181310.4103/jad.jad_142_23Cardiovascular risk factors affecting COVID-19 outcomes at a tertiary referral hospital in northwest Iran: A prospective cohort studyMahsa BehnemoonMojdeh MehrnoNaser GharebaghiMilad HamdiObjective: To investigate cardiovascular risk factors affecting COVID-19 outcomes in a tertiary referral hospital. Methods: This prospective cohort study analyzed 269 participants with COVID-19. The primary outcomes were ICU admission, prolonged hospital stay duration, and in-hospital death. The secondary outcomes included death, chronic symptoms, and NYHA functional class during follow-up periods. Results: A total of 412 patients with COVID-19 symptoms were enrolled in the study, and out of which 269 patients had complete medical records and positive SARS-CoV-2 PCR test results, fulfilling the study criteria were analyzed. The patients were divided into two groups, with cardiovascular comorbidities (group A, n=122), such as established cardiovascular disease, diabetes mellitus, and hypertension, and without cardiovascular comorbidities (group B, n=147). Binary logistic regression analysis showed that patients with underlying hypertension, diabetes, and established cardiovascular disease had a 1.55 (95% CI: 1.28-2.26), 1.62 (95% CI: 1.34-2.13), and 1.63 (95% CI: 1.07-5.34)-fold risk of mortality, respectively in the adjusted model. Conclusions: Hospitalized COVID-19 patients with predisposing cardiovascular risk factors are more susceptible to develop worse outcomes. More attention should be paid to the management and follow-up of these patients.http://www.jadweb.org/article.asp?issn=2221-6189;year=2024;volume=13;issue=1;spage=8;epage=13;aulast=Behnemooncovid-19outcomecardiovascularchronic symptomsdiabetes mellitushypertension |
| spellingShingle | Mahsa Behnemoon Mojdeh Mehrno Naser Gharebaghi Milad Hamdi Cardiovascular risk factors affecting COVID-19 outcomes at a tertiary referral hospital in northwest Iran: A prospective cohort study Journal of Acute Disease covid-19 outcome cardiovascular chronic symptoms diabetes mellitus hypertension |
| title | Cardiovascular risk factors affecting COVID-19 outcomes at a tertiary referral hospital in northwest Iran: A prospective cohort study |
| title_full | Cardiovascular risk factors affecting COVID-19 outcomes at a tertiary referral hospital in northwest Iran: A prospective cohort study |
| title_fullStr | Cardiovascular risk factors affecting COVID-19 outcomes at a tertiary referral hospital in northwest Iran: A prospective cohort study |
| title_full_unstemmed | Cardiovascular risk factors affecting COVID-19 outcomes at a tertiary referral hospital in northwest Iran: A prospective cohort study |
| title_short | Cardiovascular risk factors affecting COVID-19 outcomes at a tertiary referral hospital in northwest Iran: A prospective cohort study |
| title_sort | cardiovascular risk factors affecting covid 19 outcomes at a tertiary referral hospital in northwest iran a prospective cohort study |
| topic | covid-19 outcome cardiovascular chronic symptoms diabetes mellitus hypertension |
| url | http://www.jadweb.org/article.asp?issn=2221-6189;year=2024;volume=13;issue=1;spage=8;epage=13;aulast=Behnemoon |
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