Frequency Mixing Magnetic Detection Setup Employing Permanent Ring Magnets as a Static Offset Field Source

Frequency mixing magnetic detection (FMMD) has been explored for its applications in fields of magnetic biosensing, multiplex detection of magnetic nanoparticles (MNP) and the determination of core size distribution of MNP samples. Such applications rely on the application of a static offset magneti...

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Main Authors: Ali Mohammad Pourshahidi, Stefan Achtsnicht, Andreas Offenhäusser, Hans-Joachim Krause
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Sensors
Subjects:
Online Access:https://www.mdpi.com/1424-8220/22/22/8776
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author Ali Mohammad Pourshahidi
Stefan Achtsnicht
Andreas Offenhäusser
Hans-Joachim Krause
author_facet Ali Mohammad Pourshahidi
Stefan Achtsnicht
Andreas Offenhäusser
Hans-Joachim Krause
author_sort Ali Mohammad Pourshahidi
collection DOAJ
description Frequency mixing magnetic detection (FMMD) has been explored for its applications in fields of magnetic biosensing, multiplex detection of magnetic nanoparticles (MNP) and the determination of core size distribution of MNP samples. Such applications rely on the application of a static offset magnetic field, which is generated traditionally with an electromagnet. Such a setup requires a current source, as well as passive or active cooling strategies, which directly sets a limitation based on the portability aspect that is desired for point of care (POC) monitoring applications. In this work, a measurement head is introduced that involves the utilization of two ring-shaped permanent magnets to generate a static offset magnetic field. A steel cylinder in the ring bores homogenizes the field. By variation of the distance between the ring magnets and of the thickness of the steel cylinder, the magnitude of the magnetic field at the sample position can be adjusted. Furthermore, the measurement setup is compared to the electromagnet offset module based on measured signals and temperature behavior.
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spelling doaj.art-03de101f3fc64c7f9370aba35d4aba372023-11-24T09:55:47ZengMDPI AGSensors1424-82202022-11-012222877610.3390/s22228776Frequency Mixing Magnetic Detection Setup Employing Permanent Ring Magnets as a Static Offset Field SourceAli Mohammad Pourshahidi0Stefan Achtsnicht1Andreas Offenhäusser2Hans-Joachim Krause3Institute of Biological Information Processing, Bioelectronics (IBI-3), Forschungszentrum Jülich, 52425 Jülich, GermanyInstitute of Nano-and Biotechnologies (INB), FH Aachen University of Applied Sciences, 52428 Jülich, GermanyInstitute of Biological Information Processing, Bioelectronics (IBI-3), Forschungszentrum Jülich, 52425 Jülich, GermanyInstitute of Biological Information Processing, Bioelectronics (IBI-3), Forschungszentrum Jülich, 52425 Jülich, GermanyFrequency mixing magnetic detection (FMMD) has been explored for its applications in fields of magnetic biosensing, multiplex detection of magnetic nanoparticles (MNP) and the determination of core size distribution of MNP samples. Such applications rely on the application of a static offset magnetic field, which is generated traditionally with an electromagnet. Such a setup requires a current source, as well as passive or active cooling strategies, which directly sets a limitation based on the portability aspect that is desired for point of care (POC) monitoring applications. In this work, a measurement head is introduced that involves the utilization of two ring-shaped permanent magnets to generate a static offset magnetic field. A steel cylinder in the ring bores homogenizes the field. By variation of the distance between the ring magnets and of the thickness of the steel cylinder, the magnitude of the magnetic field at the sample position can be adjusted. Furthermore, the measurement setup is compared to the electromagnet offset module based on measured signals and temperature behavior.https://www.mdpi.com/1424-8220/22/22/8776magnetic nanoparticlesfrequency mixing magnetic detectionbiosensorsmagnetic sensors
spellingShingle Ali Mohammad Pourshahidi
Stefan Achtsnicht
Andreas Offenhäusser
Hans-Joachim Krause
Frequency Mixing Magnetic Detection Setup Employing Permanent Ring Magnets as a Static Offset Field Source
Sensors
magnetic nanoparticles
frequency mixing magnetic detection
biosensors
magnetic sensors
title Frequency Mixing Magnetic Detection Setup Employing Permanent Ring Magnets as a Static Offset Field Source
title_full Frequency Mixing Magnetic Detection Setup Employing Permanent Ring Magnets as a Static Offset Field Source
title_fullStr Frequency Mixing Magnetic Detection Setup Employing Permanent Ring Magnets as a Static Offset Field Source
title_full_unstemmed Frequency Mixing Magnetic Detection Setup Employing Permanent Ring Magnets as a Static Offset Field Source
title_short Frequency Mixing Magnetic Detection Setup Employing Permanent Ring Magnets as a Static Offset Field Source
title_sort frequency mixing magnetic detection setup employing permanent ring magnets as a static offset field source
topic magnetic nanoparticles
frequency mixing magnetic detection
biosensors
magnetic sensors
url https://www.mdpi.com/1424-8220/22/22/8776
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