Epidemiology of Mycobacterium bovis Disease in Humans, the Netherlands, 1993–2007
In the Netherlands, 1.4% of tuberculosis (TB) cases are caused by Mycobacterium bovis. After we admitted 3 patients with M. bovis infections to our reference hospital, we conducted a retrospective analysis of all M. bovis disease in the Netherlands during 1993–2007. We analyzed data from 231 patient...
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| Format: | Article |
| Language: | English |
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Centers for Disease Control and Prevention
2011-03-01
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| Series: | Emerging Infectious Diseases |
| Subjects: | |
| Online Access: | https://wwwnc.cdc.gov/eid/article/17/3/10-1111_article |
| _version_ | 1819226902424977408 |
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| author | Christof J. Majoor Cecile Magis-Escurra Jakko van Ingen Martin J. Boeree Dick van Soolingen |
| author_facet | Christof J. Majoor Cecile Magis-Escurra Jakko van Ingen Martin J. Boeree Dick van Soolingen |
| author_sort | Christof J. Majoor |
| collection | DOAJ |
| description | In the Netherlands, 1.4% of tuberculosis (TB) cases are caused by Mycobacterium bovis. After we admitted 3 patients with M. bovis infections to our reference hospital, we conducted a retrospective analysis of all M. bovis disease in the Netherlands during 1993–2007. We analyzed data from 231 patients for clinical, demographic, treatment, and outcome characteristics and for risk factors. Most patients were native Dutch (n = 138; 59.7%) or Moroccan (n = 54; 23.4%). Disease was mainly extrapulmonary (n = 136; 58.9%). Although 95 patients had pulmonary disease, person-to-person transmission did not occur, as shown by structural DNA fingerprinting analysis. Lymph node TB was more likely to develop in women (p<0.0001), whereas pulmonary M. bovis disease developed more frequently in men (p<0.0001). Diagnosis was accurate but delayed and led to inadequate treatment in 26% of the cases. Proportion of deaths from M. bovis disease was higher than that for M. tuberculosis disease. |
| first_indexed | 2024-12-23T10:32:52Z |
| format | Article |
| id | doaj.art-03e62faa7db041c0a82a355e4f37944c |
| institution | Directory Open Access Journal |
| issn | 1080-6040 1080-6059 |
| language | English |
| last_indexed | 2024-12-23T10:32:52Z |
| publishDate | 2011-03-01 |
| publisher | Centers for Disease Control and Prevention |
| record_format | Article |
| series | Emerging Infectious Diseases |
| spelling | doaj.art-03e62faa7db041c0a82a355e4f37944c2022-12-21T17:50:22ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592011-03-0117345746310.3201/eid1703.101111Epidemiology of Mycobacterium bovis Disease in Humans, the Netherlands, 1993–2007Christof J. MajoorCecile Magis-EscurraJakko van IngenMartin J. BoereeDick van SoolingenIn the Netherlands, 1.4% of tuberculosis (TB) cases are caused by Mycobacterium bovis. After we admitted 3 patients with M. bovis infections to our reference hospital, we conducted a retrospective analysis of all M. bovis disease in the Netherlands during 1993–2007. We analyzed data from 231 patients for clinical, demographic, treatment, and outcome characteristics and for risk factors. Most patients were native Dutch (n = 138; 59.7%) or Moroccan (n = 54; 23.4%). Disease was mainly extrapulmonary (n = 136; 58.9%). Although 95 patients had pulmonary disease, person-to-person transmission did not occur, as shown by structural DNA fingerprinting analysis. Lymph node TB was more likely to develop in women (p<0.0001), whereas pulmonary M. bovis disease developed more frequently in men (p<0.0001). Diagnosis was accurate but delayed and led to inadequate treatment in 26% of the cases. Proportion of deaths from M. bovis disease was higher than that for M. tuberculosis disease.https://wwwnc.cdc.gov/eid/article/17/3/10-1111_articleMycobacterium bovisM. tuberculosis diseasetuberculosis and other mycobacteriaepidemiologyM. bovisanti-TNF-α |
| spellingShingle | Christof J. Majoor Cecile Magis-Escurra Jakko van Ingen Martin J. Boeree Dick van Soolingen Epidemiology of Mycobacterium bovis Disease in Humans, the Netherlands, 1993–2007 Emerging Infectious Diseases Mycobacterium bovis M. tuberculosis disease tuberculosis and other mycobacteria epidemiology M. bovis anti-TNF-α |
| title | Epidemiology of Mycobacterium bovis Disease in Humans, the Netherlands, 1993–2007 |
| title_full | Epidemiology of Mycobacterium bovis Disease in Humans, the Netherlands, 1993–2007 |
| title_fullStr | Epidemiology of Mycobacterium bovis Disease in Humans, the Netherlands, 1993–2007 |
| title_full_unstemmed | Epidemiology of Mycobacterium bovis Disease in Humans, the Netherlands, 1993–2007 |
| title_short | Epidemiology of Mycobacterium bovis Disease in Humans, the Netherlands, 1993–2007 |
| title_sort | epidemiology of mycobacterium bovis disease in humans the netherlands 1993 2007 |
| topic | Mycobacterium bovis M. tuberculosis disease tuberculosis and other mycobacteria epidemiology M. bovis anti-TNF-α |
| url | https://wwwnc.cdc.gov/eid/article/17/3/10-1111_article |
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