Capillary Electrophoresis as a Monitoring Tool for Flow Composition Determination
Flow analysis is the science of performing quantitative analytical chemistry in flowing streams. Because of its efficiency and speed of analysis, capillary electrophoresis (CE) is a prospective method for the monitoring of a flow composition withdrawn from various processes (e.g., occurring in biore...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-08-01
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| Series: | Molecules |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1420-3049/26/16/4918 |
| _version_ | 1797522674121965568 |
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| author | Mihkel Kaljurand Piret Saar-Reismaa Merike Vaher Jelena Gorbatsova Jekaterina Mazina-Šinkar |
| author_facet | Mihkel Kaljurand Piret Saar-Reismaa Merike Vaher Jelena Gorbatsova Jekaterina Mazina-Šinkar |
| author_sort | Mihkel Kaljurand |
| collection | DOAJ |
| description | Flow analysis is the science of performing quantitative analytical chemistry in flowing streams. Because of its efficiency and speed of analysis, capillary electrophoresis (CE) is a prospective method for the monitoring of a flow composition withdrawn from various processes (e.g., occurring in bioreactors, fermentations, enzymatic assays, and microdialysis samples). However, interfacing CE to a various flow of interest requires further study. In this paper, several ingenious approaches on interfacing flow from various chemical or bioprocesses to a capillary electrophoresis instrument are reviewed. Most of these interfaces can be described as computer-controlled autosamplers. Even though most of the described interfaces waste too many samples, many interesting and important applications of the devices are reported. However, the lack of commercially available devices prevents the wide application of CE for flow analysis. On the contrary, this fact opens up a potential avenue for future research in the field of flow sampling by CE. |
| first_indexed | 2024-03-10T08:32:48Z |
| format | Article |
| id | doaj.art-03e634f958cc4c4f9f6e1aa8e689e395 |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-03-10T08:32:48Z |
| publishDate | 2021-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-03e634f958cc4c4f9f6e1aa8e689e3952023-11-22T08:53:56ZengMDPI AGMolecules1420-30492021-08-012616491810.3390/molecules26164918Capillary Electrophoresis as a Monitoring Tool for Flow Composition DeterminationMihkel Kaljurand0Piret Saar-Reismaa1Merike Vaher2Jelena Gorbatsova3Jekaterina Mazina-Šinkar4Faculty of Science, Institute of Chemistry and Biotechnology, Tallinn University of Technology, 19089 Tallinn, EstoniaFaculty of Science, Institute of Chemistry and Biotechnology, Tallinn University of Technology, 19089 Tallinn, EstoniaFaculty of Science, Institute of Chemistry and Biotechnology, Tallinn University of Technology, 19089 Tallinn, EstoniaFaculty of Science, Institute of Chemistry and Biotechnology, Tallinn University of Technology, 19089 Tallinn, EstoniaFaculty of Science, Institute of Chemistry and Biotechnology, Tallinn University of Technology, 19089 Tallinn, EstoniaFlow analysis is the science of performing quantitative analytical chemistry in flowing streams. Because of its efficiency and speed of analysis, capillary electrophoresis (CE) is a prospective method for the monitoring of a flow composition withdrawn from various processes (e.g., occurring in bioreactors, fermentations, enzymatic assays, and microdialysis samples). However, interfacing CE to a various flow of interest requires further study. In this paper, several ingenious approaches on interfacing flow from various chemical or bioprocesses to a capillary electrophoresis instrument are reviewed. Most of these interfaces can be described as computer-controlled autosamplers. Even though most of the described interfaces waste too many samples, many interesting and important applications of the devices are reported. However, the lack of commercially available devices prevents the wide application of CE for flow analysis. On the contrary, this fact opens up a potential avenue for future research in the field of flow sampling by CE.https://www.mdpi.com/1420-3049/26/16/4918flow analysismonitoringcapillary electrophoresisopen source hardware |
| spellingShingle | Mihkel Kaljurand Piret Saar-Reismaa Merike Vaher Jelena Gorbatsova Jekaterina Mazina-Šinkar Capillary Electrophoresis as a Monitoring Tool for Flow Composition Determination Molecules flow analysis monitoring capillary electrophoresis open source hardware |
| title | Capillary Electrophoresis as a Monitoring Tool for Flow Composition Determination |
| title_full | Capillary Electrophoresis as a Monitoring Tool for Flow Composition Determination |
| title_fullStr | Capillary Electrophoresis as a Monitoring Tool for Flow Composition Determination |
| title_full_unstemmed | Capillary Electrophoresis as a Monitoring Tool for Flow Composition Determination |
| title_short | Capillary Electrophoresis as a Monitoring Tool for Flow Composition Determination |
| title_sort | capillary electrophoresis as a monitoring tool for flow composition determination |
| topic | flow analysis monitoring capillary electrophoresis open source hardware |
| url | https://www.mdpi.com/1420-3049/26/16/4918 |
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