Emerging regenerative medicine for hemorrhagic stroke: An update on stem cell therapies

Hemorrhagic stroke (HS) is a disastrous occurrence with high mortality rates, however, there are no established treatments for this pathology. Given recent advances in stem cell therapies, concerted research efforts have elucidated the therapeutic potential of stem cells in treating HS. In 2020, our...

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Main Authors: Molly Monsour, Cesario V. Borlongan
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2023-03-01
Series:Brain Hemorrhages
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589238X22000389
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author Molly Monsour
Cesario V. Borlongan
author_facet Molly Monsour
Cesario V. Borlongan
author_sort Molly Monsour
collection DOAJ
description Hemorrhagic stroke (HS) is a disastrous occurrence with high mortality rates, however, there are no established treatments for this pathology. Given recent advances in stem cell therapies, concerted research efforts have elucidated the therapeutic potential of stem cells in treating HS. In 2020, our group reviewed the use of SCs in regulating the neuroinflammatory reactions which occur after HS.1 This review will build on that work, highlighting more recent advancements in the field of SC treatments for HS. Ultimately, with greater focus in this area of research, innovative SC therapies can be optimized in preclinical studies and soon be transferred to clinical applications for HS therapeutics.
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spelling doaj.art-03e6fd0028b841968feccbc7410c510b2022-12-22T04:16:06ZengKeAi Communications Co., Ltd.Brain Hemorrhages2589-238X2023-03-01412226Emerging regenerative medicine for hemorrhagic stroke: An update on stem cell therapiesMolly Monsour0Cesario V. Borlongan1University of South Florida Morsani College of Medicine, 12901 Bruce B. Downs Blvd., Tampa, FL 33612, USACenter of Excellence for Aging and Brain Repair, University of South Florida Morsani College of Medicine, 12901 Bruce B Downs Blvd., Tampa, FL 33612, USA; Corresponding author at: Center of Excellence for Aging and Brain Repair, University of South Florida Morsani College of Medicine, 12901 Bruce B Downs Blvd., Tampa, FL 33612, USA.Hemorrhagic stroke (HS) is a disastrous occurrence with high mortality rates, however, there are no established treatments for this pathology. Given recent advances in stem cell therapies, concerted research efforts have elucidated the therapeutic potential of stem cells in treating HS. In 2020, our group reviewed the use of SCs in regulating the neuroinflammatory reactions which occur after HS.1 This review will build on that work, highlighting more recent advancements in the field of SC treatments for HS. Ultimately, with greater focus in this area of research, innovative SC therapies can be optimized in preclinical studies and soon be transferred to clinical applications for HS therapeutics.http://www.sciencedirect.com/science/article/pii/S2589238X22000389Hemorrhagic strokeStem cells
spellingShingle Molly Monsour
Cesario V. Borlongan
Emerging regenerative medicine for hemorrhagic stroke: An update on stem cell therapies
Brain Hemorrhages
Hemorrhagic stroke
Stem cells
title Emerging regenerative medicine for hemorrhagic stroke: An update on stem cell therapies
title_full Emerging regenerative medicine for hemorrhagic stroke: An update on stem cell therapies
title_fullStr Emerging regenerative medicine for hemorrhagic stroke: An update on stem cell therapies
title_full_unstemmed Emerging regenerative medicine for hemorrhagic stroke: An update on stem cell therapies
title_short Emerging regenerative medicine for hemorrhagic stroke: An update on stem cell therapies
title_sort emerging regenerative medicine for hemorrhagic stroke an update on stem cell therapies
topic Hemorrhagic stroke
Stem cells
url http://www.sciencedirect.com/science/article/pii/S2589238X22000389
work_keys_str_mv AT mollymonsour emergingregenerativemedicineforhemorrhagicstrokeanupdateonstemcelltherapies
AT cesariovborlongan emergingregenerativemedicineforhemorrhagicstrokeanupdateonstemcelltherapies