Differential Impacts on Host Transcription by ROP and GRA Effectors from the Intracellular Parasite <named-content content-type="genus-species">Toxoplasma gondii</named-content>

Differential Impacts on Host Transcription by ROP and GRA Effectors from the Intracellular Parasite <named-content content-type="genus-species">Toxoplasma gondii</named-content>

ABSTRACT The intracellular parasite Toxoplasma gondii employs a vast array of effector proteins from the rhoptry and dense granule organelles to modulate host cell biology; these effectors are known as ROPs and GRAs, respectively. To examine the individual impacts of ROPs and GRAs on host gene expre...

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Bibliographic Details
Main Authors: Suchita Rastogi, Yuan Xue, Stephen R. Quake, John C. Boothroyd
Format: Article
Language:English
Published: American Society for Microbiology 2020-06-01
Series:mBio
Subjects:
Toxoplasma
effector functions
host-parasite relationship
parasitology
single-cell RNA sequencing
Online Access:https://journals.asm.org/doi/10.1128/mBio.00182-20

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