Inhalable, Spray-Dried Terbinafine Microparticles for Management of Pulmonary Fungal Infections: Optimization of the Excipient Composition and Selection of an Inhalation Device

Inhalable, Spray-Dried Terbinafine Microparticles for Management of Pulmonary Fungal Infections: Optimization of the Excipient Composition and Selection of an Inhalation Device

Terbinafine is a broad-spectrum antifungal agent with therapeutic potential against pulmonary aspergillosis. The main aim of the current study was to investigate the potential of <span style="font-variant: small-caps;">l</span>-leucine, alone and in combination with mannitol, t...

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Bibliographic Details
Main Authors: Khaled Almansour, Iman M. Alfagih, Alhassan H. Aodah, Fawaz Alheibshy, Raisuddin Ali, Turki Al Hagbani, Mustafa M.A. Elsayed
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Pharmaceutics
Subjects:
dry powder inhalation
nano spray drying
terbinafine
pulmonary aspergillosis
leucine
mannitol
Online Access:https://www.mdpi.com/1999-4923/14/1/87

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