Bone-Demineralized bone-Bone Grafts for Ligament Reconstruction
Ligament reconstruction with the use of novel demineralized bone grafts was investigated in a rabbit model. By demineralizing only the central portions of the long bone samples, the grafts had a configuration of the bone-tendon-bone graft and were flexible in bending. Strip type grafts made from fem...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
The Japan Society of Mechanical Engineers
2007-04-01
|
| Series: | Journal of Biomechanical Science and Engineering |
| Subjects: | |
| Online Access: | https://www.jstage.jst.go.jp/article/jbse/2/1/2_1_23/_pdf/-char/en |
| _version_ | 1811296788033830912 |
|---|---|
| author | Takeki YAMADA Yoshihisa KOYAMA Tomoyuki KAWAI Takeshi MUNETA Kazuo TAKAKUDA |
| author_facet | Takeki YAMADA Yoshihisa KOYAMA Tomoyuki KAWAI Takeshi MUNETA Kazuo TAKAKUDA |
| author_sort | Takeki YAMADA |
| collection | DOAJ |
| description | Ligament reconstruction with the use of novel demineralized bone grafts was investigated in a rabbit model. By demineralizing only the central portions of the long bone samples, the grafts had a configuration of the bone-tendon-bone graft and were flexible in bending. Strip type grafts made from femur, stick type grafts from tibia, and tube type grafts from metacarpal bones were prepared and their performances were evaluated by tensile testing and animal experiments for medial collateral ligament (MCL) and anterior cruciate ligament (ACL) reconstruction. The maximum strength of the strip and stick type grafts were about half of that of MCL, and that of tube type grafts was also about half of that of ACL. The survival rate of strip type grafts in MCL reconstruction was about 50%, and that of stick type was about 60%. In ACL reconstruction, the survival rate of strip type grafts was 0%, that of stick type was 10%, whereas that of tube type grafts was 50%, and that of tube type grafts reinforced with suture was 60%. The strip and stick type grafts might be useful for MCL reconstruction and the tube type grafts might be available for ACL reconstruction with suitable reinforcements. |
| first_indexed | 2024-04-13T05:54:37Z |
| format | Article |
| id | doaj.art-03ec29c6a8784050889462b4ee343f85 |
| institution | Directory Open Access Journal |
| issn | 1880-9863 |
| language | English |
| last_indexed | 2024-04-13T05:54:37Z |
| publishDate | 2007-04-01 |
| publisher | The Japan Society of Mechanical Engineers |
| record_format | Article |
| series | Journal of Biomechanical Science and Engineering |
| spelling | doaj.art-03ec29c6a8784050889462b4ee343f852022-12-22T02:59:40ZengThe Japan Society of Mechanical EngineersJournal of Biomechanical Science and Engineering1880-98632007-04-0121233310.1299/jbse.2.23jbseBone-Demineralized bone-Bone Grafts for Ligament ReconstructionTakeki YAMADA0Yoshihisa KOYAMA1Tomoyuki KAWAI2Takeshi MUNETA3Kazuo TAKAKUDA4Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental UniversityInstitute of Biomaterials and Bioengineering, Tokyo Medical and Dental UniversityInstitute of Biomaterials and Bioengineering, Tokyo Medical and Dental UniversityDepartment of Orthopedic Surgery, Tokyo Medical and Dental UniversityInstitute of Biomaterials and Bioengineering, Tokyo Medical and Dental UniversityLigament reconstruction with the use of novel demineralized bone grafts was investigated in a rabbit model. By demineralizing only the central portions of the long bone samples, the grafts had a configuration of the bone-tendon-bone graft and were flexible in bending. Strip type grafts made from femur, stick type grafts from tibia, and tube type grafts from metacarpal bones were prepared and their performances were evaluated by tensile testing and animal experiments for medial collateral ligament (MCL) and anterior cruciate ligament (ACL) reconstruction. The maximum strength of the strip and stick type grafts were about half of that of MCL, and that of tube type grafts was also about half of that of ACL. The survival rate of strip type grafts in MCL reconstruction was about 50%, and that of stick type was about 60%. In ACL reconstruction, the survival rate of strip type grafts was 0%, that of stick type was 10%, whereas that of tube type grafts was 50%, and that of tube type grafts reinforced with suture was 60%. The strip and stick type grafts might be useful for MCL reconstruction and the tube type grafts might be available for ACL reconstruction with suitable reinforcements.https://www.jstage.jst.go.jp/article/jbse/2/1/2_1_23/_pdf/-char/enligament reconstructionbtb graftsbiological materialscollagendemineralized bonemechanical property |
| spellingShingle | Takeki YAMADA Yoshihisa KOYAMA Tomoyuki KAWAI Takeshi MUNETA Kazuo TAKAKUDA Bone-Demineralized bone-Bone Grafts for Ligament Reconstruction Journal of Biomechanical Science and Engineering ligament reconstruction btb grafts biological materials collagen demineralized bone mechanical property |
| title | Bone-Demineralized bone-Bone Grafts for Ligament Reconstruction |
| title_full | Bone-Demineralized bone-Bone Grafts for Ligament Reconstruction |
| title_fullStr | Bone-Demineralized bone-Bone Grafts for Ligament Reconstruction |
| title_full_unstemmed | Bone-Demineralized bone-Bone Grafts for Ligament Reconstruction |
| title_short | Bone-Demineralized bone-Bone Grafts for Ligament Reconstruction |
| title_sort | bone demineralized bone bone grafts for ligament reconstruction |
| topic | ligament reconstruction btb grafts biological materials collagen demineralized bone mechanical property |
| url | https://www.jstage.jst.go.jp/article/jbse/2/1/2_1_23/_pdf/-char/en |
| work_keys_str_mv | AT takekiyamada bonedemineralizedbonebonegraftsforligamentreconstruction AT yoshihisakoyama bonedemineralizedbonebonegraftsforligamentreconstruction AT tomoyukikawai bonedemineralizedbonebonegraftsforligamentreconstruction AT takeshimuneta bonedemineralizedbonebonegraftsforligamentreconstruction AT kazuotakakuda bonedemineralizedbonebonegraftsforligamentreconstruction |