Evolutionary shaping of human brain dynamics
The human brain is distinct from those of other species in terms of size, organization, and connectivity. How do structural evolutionary differences drive patterns of neural activity enabling brain function? Here, we combine brain imaging and biophysical modeling to show that the anatomical wiring o...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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eLife Sciences Publications Ltd
2022-10-01
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| Series: | eLife |
| Subjects: | |
| Online Access: | https://elifesciences.org/articles/80627 |
| _version_ | 1811221256834383872 |
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| author | James C Pang James K Rilling James A Roberts Martijn P van den Heuvel Luca Cocchi |
| author_facet | James C Pang James K Rilling James A Roberts Martijn P van den Heuvel Luca Cocchi |
| author_sort | James C Pang |
| collection | DOAJ |
| description | The human brain is distinct from those of other species in terms of size, organization, and connectivity. How do structural evolutionary differences drive patterns of neural activity enabling brain function? Here, we combine brain imaging and biophysical modeling to show that the anatomical wiring of the human brain distinctly shapes neural dynamics. This shaping is characterized by a narrower distribution of dynamic ranges across brain regions compared with that of chimpanzees, our closest living primate relatives. We find that such a narrow dynamic range distribution supports faster integration between regions, particularly in transmodal systems. Conversely, a broad dynamic range distribution as seen in chimpanzees facilitates brain processes relying more on neural interactions within specialized local brain systems. These findings suggest that human brain dynamics have evolved to foster rapid associative processes in service of complex cognitive functions and behavior. |
| first_indexed | 2024-04-12T07:56:13Z |
| format | Article |
| id | doaj.art-03f09140ffec46509d17cf7c56fe794e |
| institution | Directory Open Access Journal |
| issn | 2050-084X |
| language | English |
| last_indexed | 2024-04-12T07:56:13Z |
| publishDate | 2022-10-01 |
| publisher | eLife Sciences Publications Ltd |
| record_format | Article |
| series | eLife |
| spelling | doaj.art-03f09140ffec46509d17cf7c56fe794e2022-12-22T03:41:28ZengeLife Sciences Publications LtdeLife2050-084X2022-10-011110.7554/eLife.80627Evolutionary shaping of human brain dynamicsJames C Pang0https://orcid.org/0000-0002-2461-2760James K Rilling1James A Roberts2Martijn P van den Heuvel3Luca Cocchi4https://orcid.org/0000-0003-3651-2676The Turner Institute for Brain and Mental Health, School of Psychological Sciences, and Monash Biomedical Imaging, Monash University, Victoria, Australia; QIMR Berghofer Medical Research Institute, Queensland, AustraliaDepartment of Anthropology, Emory University, Atlanta, United States; Department of Psychiatry and Behavioral Sciences, Emory University, Atlanta, United States; Yerkes National Primate Research Center, Emory University, Atlanta, United StatesQIMR Berghofer Medical Research Institute, Queensland, AustraliaDepartment of Complex Traits Genetics, Center for Neurogenetics and Cognitive Research, Vrije Universiteit Amsterdam, Amsterdam, Netherlands; Department of Clinical Genetics, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, NetherlandsQIMR Berghofer Medical Research Institute, Queensland, AustraliaThe human brain is distinct from those of other species in terms of size, organization, and connectivity. How do structural evolutionary differences drive patterns of neural activity enabling brain function? Here, we combine brain imaging and biophysical modeling to show that the anatomical wiring of the human brain distinctly shapes neural dynamics. This shaping is characterized by a narrower distribution of dynamic ranges across brain regions compared with that of chimpanzees, our closest living primate relatives. We find that such a narrow dynamic range distribution supports faster integration between regions, particularly in transmodal systems. Conversely, a broad dynamic range distribution as seen in chimpanzees facilitates brain processes relying more on neural interactions within specialized local brain systems. These findings suggest that human brain dynamics have evolved to foster rapid associative processes in service of complex cognitive functions and behavior.https://elifesciences.org/articles/80627brain dynamicsevolutionconnectomecomputational modelingchimpanzee |
| spellingShingle | James C Pang James K Rilling James A Roberts Martijn P van den Heuvel Luca Cocchi Evolutionary shaping of human brain dynamics eLife brain dynamics evolution connectome computational modeling chimpanzee |
| title | Evolutionary shaping of human brain dynamics |
| title_full | Evolutionary shaping of human brain dynamics |
| title_fullStr | Evolutionary shaping of human brain dynamics |
| title_full_unstemmed | Evolutionary shaping of human brain dynamics |
| title_short | Evolutionary shaping of human brain dynamics |
| title_sort | evolutionary shaping of human brain dynamics |
| topic | brain dynamics evolution connectome computational modeling chimpanzee |
| url | https://elifesciences.org/articles/80627 |
| work_keys_str_mv | AT jamescpang evolutionaryshapingofhumanbraindynamics AT jameskrilling evolutionaryshapingofhumanbraindynamics AT jamesaroberts evolutionaryshapingofhumanbraindynamics AT martijnpvandenheuvel evolutionaryshapingofhumanbraindynamics AT lucacocchi evolutionaryshapingofhumanbraindynamics |