Prevalence of renal tubular dysfunction in beta thalassemia minor in shiraz

Background & objective: β-Thalassemia minor is an asymptomatic hereditary disease. The first study on the relation of renal tubular dysfunction and β-thalassemia minor was performed in 2002 but those studies seem inadequate.The main goal of this study is through evaluation of renal tubular funct...

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Main Authors: Ali Moradi Nakhodcheri, Mohammad Ali Yaghut
Format: Article
Language:fas
Published: Fasa University of Medical Sciences 2012-02-01
Series:Journal of Fasa University of Medical Sciences
Subjects:
Online Access:http://journal.fums.ac.ir/browse.php?a_code=A-10-1-60&slc_lang=en&sid=1
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author Ali Moradi Nakhodcheri
Mohammad Ali Yaghut
author_facet Ali Moradi Nakhodcheri
Mohammad Ali Yaghut
author_sort Ali Moradi Nakhodcheri
collection DOAJ
description Background & objective: β-Thalassemia minor is an asymptomatic hereditary disease. The first study on the relation of renal tubular dysfunction and β-thalassemia minor was performed in 2002 but those studies seem inadequate.The main goal of this study is through evaluation of renal tubular function in 100 patients with thalassemia minor. Materials & Methods: 100 patients with β- thalassemia which confirmed by hemoglobin electrophoresis and CBC as well as RBC indices were studied.14 out of 100 cases exit because of Urinary Tract Infection, diabetes mellitus or hypertension.Complete chemistry profile was performed on serum and urine of all reminder 86 patients (46 female and 40 male). Patients classified into two groups: β-thalassemia minor with anemia and without anemia. Another control group include 50 healthy individuals also considered.Then data analyzed by proper statistical methods. Results: 20 out of 86 reminder cases e.g. 24% showed at least one index of renal tubular dysfunction.58% of patients was been anemic and 42% non anemic. The most prominent tubular dysfunction was seen in a 29 years old lady with glucosuria and without anemia. conclusion: β-Thalassemia minor is common in Iran specially in Fars province. This study revealed significant renal tubular dysfunction in patient with β-thalassemia minor. So it is necessary to check out thalassemic patients for renal function tests periodically. Key words: β-thalassemia, minor,renal tubular dysfunction
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spelling doaj.art-03f250638b7d40db9491f04f1446c3142022-12-21T23:31:01ZfasFasa University of Medical SciencesJournal of Fasa University of Medical Sciences2228-51052228-73292012-02-0114192196Prevalence of renal tubular dysfunction in beta thalassemia minor in shirazAli Moradi NakhodcheriMohammad Ali YaghutBackground & objective: β-Thalassemia minor is an asymptomatic hereditary disease. The first study on the relation of renal tubular dysfunction and β-thalassemia minor was performed in 2002 but those studies seem inadequate.The main goal of this study is through evaluation of renal tubular function in 100 patients with thalassemia minor. Materials & Methods: 100 patients with β- thalassemia which confirmed by hemoglobin electrophoresis and CBC as well as RBC indices were studied.14 out of 100 cases exit because of Urinary Tract Infection, diabetes mellitus or hypertension.Complete chemistry profile was performed on serum and urine of all reminder 86 patients (46 female and 40 male). Patients classified into two groups: β-thalassemia minor with anemia and without anemia. Another control group include 50 healthy individuals also considered.Then data analyzed by proper statistical methods. Results: 20 out of 86 reminder cases e.g. 24% showed at least one index of renal tubular dysfunction.58% of patients was been anemic and 42% non anemic. The most prominent tubular dysfunction was seen in a 29 years old lady with glucosuria and without anemia. conclusion: β-Thalassemia minor is common in Iran specially in Fars province. This study revealed significant renal tubular dysfunction in patient with β-thalassemia minor. So it is necessary to check out thalassemic patients for renal function tests periodically. Key words: β-thalassemia, minor,renal tubular dysfunctionhttp://journal.fums.ac.ir/browse.php?a_code=A-10-1-60&slc_lang=en&sid=1β-thalassemiaminorrenal tubular dysfunction
spellingShingle Ali Moradi Nakhodcheri
Mohammad Ali Yaghut
Prevalence of renal tubular dysfunction in beta thalassemia minor in shiraz
Journal of Fasa University of Medical Sciences
β-thalassemia
minor
renal tubular dysfunction
title Prevalence of renal tubular dysfunction in beta thalassemia minor in shiraz
title_full Prevalence of renal tubular dysfunction in beta thalassemia minor in shiraz
title_fullStr Prevalence of renal tubular dysfunction in beta thalassemia minor in shiraz
title_full_unstemmed Prevalence of renal tubular dysfunction in beta thalassemia minor in shiraz
title_short Prevalence of renal tubular dysfunction in beta thalassemia minor in shiraz
title_sort prevalence of renal tubular dysfunction in beta thalassemia minor in shiraz
topic β-thalassemia
minor
renal tubular dysfunction
url http://journal.fums.ac.ir/browse.php?a_code=A-10-1-60&slc_lang=en&sid=1
work_keys_str_mv AT alimoradinakhodcheri prevalenceofrenaltubulardysfunctioninbetathalassemiaminorinshiraz
AT mohammadaliyaghut prevalenceofrenaltubulardysfunctioninbetathalassemiaminorinshiraz