ChIPr: accurate prediction of cohesin-mediated 3D genome organization from 2D chromatin features

Abstract The three-dimensional genome organization influences diverse nuclear processes. Here we present Chromatin Interaction Predictor (ChIPr), a suite of regression models based on deep neural networks, random forest, and gradient boosting to predict cohesin-mediated chromatin interaction strengt...

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Bibliographic Details
Main Authors: Ahmed Abbas, Khyati Chandratre, Yunpeng Gao, Jiapei Yuan, Michael Q. Zhang, Ram S. Mani
Format: Article
Language:English
Published: BMC 2024-01-01
Series:Genome Biology
Online Access:https://doi.org/10.1186/s13059-023-03158-7

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