ChIPr: accurate prediction of cohesin-mediated 3D genome organization from 2D chromatin features
Abstract The three-dimensional genome organization influences diverse nuclear processes. Here we present Chromatin Interaction Predictor (ChIPr), a suite of regression models based on deep neural networks, random forest, and gradient boosting to predict cohesin-mediated chromatin interaction strengt...
Main Authors: | Ahmed Abbas, Khyati Chandratre, Yunpeng Gao, Jiapei Yuan, Michael Q. Zhang, Ram S. Mani |
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Format: | Article |
Language: | English |
Published: |
BMC
2024-01-01
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Series: | Genome Biology |
Online Access: | https://doi.org/10.1186/s13059-023-03158-7 |
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