Surveillance of hospitalizations with pandemic A(H1N1) 2009 influenza infection in Queensland, Australia
Objective : To describe the demographic and clinical characteristics of patients hospitalized with pandemic A(H1N1) 2009 infection in Queensland, Australia between 25 May and 3 October 2009 and to examine the relationship between timing of antiviral treatment and severity of illness.Method: Using da...
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| Format: | Article |
| Language: | English |
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World Health Organization Regional Office for the Western Pacific
2011-05-01
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| Series: | Western Pacific Surveillance and Response |
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| Online Access: | http://ojs.wpro.who.int/ojs/index.php/wpsar/article/view/120/43 |
| _version_ | 1818644617783934976 |
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| author | Frances Birrell Ranil Appuhamy Frances Birrell Christine Selvey Ranil Appuhamy Christine Selvey Frank Beard Frank Beard Hai Phung Hai Phung |
| author_facet | Frances Birrell Ranil Appuhamy Frances Birrell Christine Selvey Ranil Appuhamy Christine Selvey Frank Beard Frank Beard Hai Phung Hai Phung |
| author_sort | Frances Birrell |
| collection | DOAJ |
| description | Objective : To describe the demographic and clinical characteristics of patients hospitalized with pandemic A(H1N1) 2009 infection in Queensland, Australia between 25 May and 3 October 2009 and to examine the relationship between timing of antiviral treatment and severity of illness.Method: Using data from the Queensland Health EpiLog information system, descriptive analysis and logistic regression modelling were used to describe and model factors which influence patient outcomes (death, admission to intensive care unit and/or special care unit). Data on patients admitted to hospital in Queensland with confirmed pandemic A(H1N1) 2009 infection were included in this analysis.Results: 1236 patients with pandemic A(H1N1) 2009 infection were admitted to hospitals in Queensland during the study period. Of the total group: 15% were admitted to an intensive care unit or special care unit; 3% died; 34% were under the age of 18 years and 8% were 65 years of age or older; and 55% had at least one underlying medical condition. Among the 842 patients for whom data were available regarding the use of antiviral drugs, antiviral treatment was initiated in 737 (87.5%) patients with treatment commencing at a median of one day (range 1–33 days) after onset of illness. Admission to an intensive care unit or special care unit (ICU/SCU) or death was significantly associated with increased age, lack of timeliness of antiviral treatment, chronic renal disease and morbid obesity.Discussion: Early antiviral treatment was significantly associated with lower likelihood of ICU/SCU admission or death. Early antiviral treatment for influenza cases may therefore have important public health implications. |
| first_indexed | 2024-12-17T00:17:42Z |
| format | Article |
| id | doaj.art-04027048bf5540f991e0c1ab096cefe4 |
| institution | Directory Open Access Journal |
| issn | 2094-7321 2094-7313 |
| language | English |
| last_indexed | 2024-12-17T00:17:42Z |
| publishDate | 2011-05-01 |
| publisher | World Health Organization Regional Office for the Western Pacific |
| record_format | Article |
| series | Western Pacific Surveillance and Response |
| spelling | doaj.art-04027048bf5540f991e0c1ab096cefe42022-12-21T22:10:39ZengWorld Health Organization Regional Office for the Western PacificWestern Pacific Surveillance and Response2094-73212094-73132011-05-0122303510.5365/wpsar.2010.1.1.013Surveillance of hospitalizations with pandemic A(H1N1) 2009 influenza infection in Queensland, AustraliaFrances BirrellRanil AppuhamyFrances BirrellChristine SelveyRanil AppuhamyChristine SelveyFrank BeardFrank BeardHai PhungHai PhungObjective : To describe the demographic and clinical characteristics of patients hospitalized with pandemic A(H1N1) 2009 infection in Queensland, Australia between 25 May and 3 October 2009 and to examine the relationship between timing of antiviral treatment and severity of illness.Method: Using data from the Queensland Health EpiLog information system, descriptive analysis and logistic regression modelling were used to describe and model factors which influence patient outcomes (death, admission to intensive care unit and/or special care unit). Data on patients admitted to hospital in Queensland with confirmed pandemic A(H1N1) 2009 infection were included in this analysis.Results: 1236 patients with pandemic A(H1N1) 2009 infection were admitted to hospitals in Queensland during the study period. Of the total group: 15% were admitted to an intensive care unit or special care unit; 3% died; 34% were under the age of 18 years and 8% were 65 years of age or older; and 55% had at least one underlying medical condition. Among the 842 patients for whom data were available regarding the use of antiviral drugs, antiviral treatment was initiated in 737 (87.5%) patients with treatment commencing at a median of one day (range 1–33 days) after onset of illness. Admission to an intensive care unit or special care unit (ICU/SCU) or death was significantly associated with increased age, lack of timeliness of antiviral treatment, chronic renal disease and morbid obesity.Discussion: Early antiviral treatment was significantly associated with lower likelihood of ICU/SCU admission or death. Early antiviral treatment for influenza cases may therefore have important public health implications.http://ojs.wpro.who.int/ojs/index.php/wpsar/article/view/120/43pandemicH1N1infectionQueenslandAustralia |
| spellingShingle | Frances Birrell Ranil Appuhamy Frances Birrell Christine Selvey Ranil Appuhamy Christine Selvey Frank Beard Frank Beard Hai Phung Hai Phung Surveillance of hospitalizations with pandemic A(H1N1) 2009 influenza infection in Queensland, Australia Western Pacific Surveillance and Response pandemic H1N1 infection Queensland Australia |
| title | Surveillance of hospitalizations with pandemic A(H1N1) 2009 influenza infection in Queensland, Australia |
| title_full | Surveillance of hospitalizations with pandemic A(H1N1) 2009 influenza infection in Queensland, Australia |
| title_fullStr | Surveillance of hospitalizations with pandemic A(H1N1) 2009 influenza infection in Queensland, Australia |
| title_full_unstemmed | Surveillance of hospitalizations with pandemic A(H1N1) 2009 influenza infection in Queensland, Australia |
| title_short | Surveillance of hospitalizations with pandemic A(H1N1) 2009 influenza infection in Queensland, Australia |
| title_sort | surveillance of hospitalizations with pandemic a h1n1 2009 influenza infection in queensland australia |
| topic | pandemic H1N1 infection Queensland Australia |
| url | http://ojs.wpro.who.int/ojs/index.php/wpsar/article/view/120/43 |
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