<italic toggle="yes">Clostridium difficile</italic> Alters the Structure and Metabolism of Distinct Cecal Microbiomes during Initial Infection To Promote Sustained Colonization

<italic toggle="yes">Clostridium difficile</italic> Alters the Structure and Metabolism of Distinct Cecal Microbiomes during Initial Infection To Promote Sustained Colonization

ABSTRACT Susceptibility to Clostridium difficile infection (CDI) is primarily associated with previous exposure to antibiotics, which compromise the structure and function of the gut bacterial community. Specific antibiotic classes correlate more strongly with recurrent or persistent C. difficile in...

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Bibliographic Details
Main Authors: Matthew L. Jenior, Jhansi L. Leslie, Vincent B. Young, Patrick D. Schloss
Format: Article
Language:English
Published: American Society for Microbiology 2018-06-01
Series:mSphere
Subjects:
16S rRNA gene sequencing
Clostridium difficile
colonization resistance
machine learning
microbiome
systems biology
Online Access:https://journals.asm.org/doi/10.1128/mSphere.00261-18

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