Efficacy of single-shot adductor canal block before Versus after primary total knee arthroplasty – Does timing make a difference? A randomized controlled trial

Background Total knee arthroplasty (TKA) is associated with severe postoperative pain. Multimodal analgesia, including peripheral nerve block, is recommended for post-operative pain relief. Administration of some pain medications prior to surgery has shown to be more effective than after the operati...

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Main Authors: Snir Heller, Shai Shemesh, Oleg Rukinglaz, Nir Cohen, Steven Velkes, Shai Fein
Format: Article
Language:English
Published: SAGE Publishing 2022-10-01
Series:Journal of Orthopaedic Surgery
Online Access:https://doi.org/10.1177/10225536221132050
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author Snir Heller
Shai Shemesh
Oleg Rukinglaz
Nir Cohen
Steven Velkes
Shai Fein
author_facet Snir Heller
Shai Shemesh
Oleg Rukinglaz
Nir Cohen
Steven Velkes
Shai Fein
author_sort Snir Heller
collection DOAJ
description Background Total knee arthroplasty (TKA) is associated with severe postoperative pain. Multimodal analgesia, including peripheral nerve block, is recommended for post-operative pain relief. Administration of some pain medications prior to surgery has shown to be more effective than after the operation. This is a prospective, randomized controlled trial designed to compare the analgesic efficacy of the adductor canal block (ACB) performed immediately before or immediately after primary total knee arthroplasty (TKA). We hypothesized that ACB before the surgery will reduce postoperative pain and improve knee function. Methods A total of 50 patients were enrolled and randomized into 2 groups, with 26 patients receiving a preoperative ACB and 24 receiving a postoperative ACB. Results Treatment groups were similar in terms of gender ( p = .83), age ( p = 0.61) weight ( p = .39) and ASA score. Average visual analogue scale (VAS) on arrival to the post-anesthesia care unit (PACU) were 4.9 ± 3.2 in the preoperative ACB versus 3.4 ± 2.8 for the postoperative ACB ( p = .075). VAS scores at different time points as well as the mean, minimal and maximal reported VAS scores were not significantly different between the two groups. The cumulative quantities of Fentanyl administered by the anesthesia team was comparable between the groups. Similarly, the dosage of Morphine, Tramadol, Acetaminophen and Dipyrone showed only small variations. The Quality of Recovery Score, Knee Society Scores and knee range of motion did not differ between the groups. Conclusions Our findings demonstrate no significant differences in patient total narcotics consumption, pain scores and functional scores, between preoperative and postoperative ACB in patients undergoing TKA. Trial Registration The trial was registered at www.clinicaltrials.gov and was assigned the registration number NCT02908711 Level of Evidence level I randomized controlled trial.
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spelling doaj.art-04041be22e9342e2bffb8e81fd01c5d42022-12-22T04:32:06ZengSAGE PublishingJournal of Orthopaedic Surgery2309-49902022-10-013010.1177/10225536221132050Efficacy of single-shot adductor canal block before Versus after primary total knee arthroplasty – Does timing make a difference? A randomized controlled trialSnir HellerShai ShemeshOleg RukinglazNir CohenSteven VelkesShai FeinBackground Total knee arthroplasty (TKA) is associated with severe postoperative pain. Multimodal analgesia, including peripheral nerve block, is recommended for post-operative pain relief. Administration of some pain medications prior to surgery has shown to be more effective than after the operation. This is a prospective, randomized controlled trial designed to compare the analgesic efficacy of the adductor canal block (ACB) performed immediately before or immediately after primary total knee arthroplasty (TKA). We hypothesized that ACB before the surgery will reduce postoperative pain and improve knee function. Methods A total of 50 patients were enrolled and randomized into 2 groups, with 26 patients receiving a preoperative ACB and 24 receiving a postoperative ACB. Results Treatment groups were similar in terms of gender ( p = .83), age ( p = 0.61) weight ( p = .39) and ASA score. Average visual analogue scale (VAS) on arrival to the post-anesthesia care unit (PACU) were 4.9 ± 3.2 in the preoperative ACB versus 3.4 ± 2.8 for the postoperative ACB ( p = .075). VAS scores at different time points as well as the mean, minimal and maximal reported VAS scores were not significantly different between the two groups. The cumulative quantities of Fentanyl administered by the anesthesia team was comparable between the groups. Similarly, the dosage of Morphine, Tramadol, Acetaminophen and Dipyrone showed only small variations. The Quality of Recovery Score, Knee Society Scores and knee range of motion did not differ between the groups. Conclusions Our findings demonstrate no significant differences in patient total narcotics consumption, pain scores and functional scores, between preoperative and postoperative ACB in patients undergoing TKA. Trial Registration The trial was registered at www.clinicaltrials.gov and was assigned the registration number NCT02908711 Level of Evidence level I randomized controlled trial.https://doi.org/10.1177/10225536221132050
spellingShingle Snir Heller
Shai Shemesh
Oleg Rukinglaz
Nir Cohen
Steven Velkes
Shai Fein
Efficacy of single-shot adductor canal block before Versus after primary total knee arthroplasty – Does timing make a difference? A randomized controlled trial
Journal of Orthopaedic Surgery
title Efficacy of single-shot adductor canal block before Versus after primary total knee arthroplasty – Does timing make a difference? A randomized controlled trial
title_full Efficacy of single-shot adductor canal block before Versus after primary total knee arthroplasty – Does timing make a difference? A randomized controlled trial
title_fullStr Efficacy of single-shot adductor canal block before Versus after primary total knee arthroplasty – Does timing make a difference? A randomized controlled trial
title_full_unstemmed Efficacy of single-shot adductor canal block before Versus after primary total knee arthroplasty – Does timing make a difference? A randomized controlled trial
title_short Efficacy of single-shot adductor canal block before Versus after primary total knee arthroplasty – Does timing make a difference? A randomized controlled trial
title_sort efficacy of single shot adductor canal block before versus after primary total knee arthroplasty does timing make a difference a randomized controlled trial
url https://doi.org/10.1177/10225536221132050
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