Age-related changes of dental pulp tissue after experimental tooth movement in rats
It is generally accepted that the effect of orthodontic tooth movement on the dental pulp in adolescents is reversible and that it has no long-lasting effect on pulpal physiology. However, it is not clear yet if the same conclusion is also valid for adult subjects. Thus, in two groups of rats, aged...
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PeerJ Inc.
2016-01-01
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| author | Martina Von Böhl Yijin Ren Anne M. Kuijpers-Jagtman Piotr S. Fudalej Jaap C. Maltha |
| author_facet | Martina Von Böhl Yijin Ren Anne M. Kuijpers-Jagtman Piotr S. Fudalej Jaap C. Maltha |
| author_sort | Martina Von Böhl |
| collection | DOAJ |
| description | It is generally accepted that the effect of orthodontic tooth movement on the dental pulp in adolescents is reversible and that it has no long-lasting effect on pulpal physiology. However, it is not clear yet if the same conclusion is also valid for adult subjects. Thus, in two groups of rats, aged 6 and 40 weeks respectively, 3 molars at one side of the maxilla were moved together in a mesial direction with a standardized orthodontic appliance delivering a force of 10 cN. The contralateral side served as a control. Parasagittal histological sections were prepared after tooth movement for 1, 2, 4, 8, and 12 weeks. The pulp tissue was characterized for the different groups, with special emphasis on cell density, inflammatory cells, vascularity, and odontoblasts. Dimensions of dentin and the pulpal horns was determined and related with the duration of orthodontic force application and age ware evaluated. We found that neither in young nor in adult rats, force application led to long-lasting or irreversible changes in pulpal tissues. Dimensional variables showed significant age-related changes. In conclusion, orthodontic tooth movement per se has no long-lasting or irreversible effect on pulpal tissues, neither in the young nor in the adult animals. |
| first_indexed | 2024-03-09T06:37:48Z |
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| institution | Directory Open Access Journal |
| issn | 2167-8359 |
| language | English |
| last_indexed | 2024-03-09T06:37:48Z |
| publishDate | 2016-01-01 |
| publisher | PeerJ Inc. |
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| spelling | doaj.art-04060bcc8b324aaf8a35f32b94a1a73d2023-12-03T10:54:59ZengPeerJ Inc.PeerJ2167-83592016-01-014e162510.7717/peerj.1625Age-related changes of dental pulp tissue after experimental tooth movement in ratsMartina Von Böhl0Yijin Ren1Anne M. Kuijpers-Jagtman2Piotr S. Fudalej3Jaap C. Maltha4Department of Orthodontics and Craniofacial Biology, Radboud University Nijmegen, Nijmegen, The NetherlandsDepartment of Orthodontics, University of Groningen, University Medical Centre Groningen, Groningen, Griningen, The NetherlandsDepartment of Orthodontics and Craniofacial Biology, Radboud University Nijmegen, Nijmegen, The NetherlandsDepartment of Orthodontics and Dentofacial Orthopedics, University of Bern, Bern, SwitzerlandDepartment of Orthodontics and Craniofacial Biology, Radboud University Nijmegen, Nijmegen, The NetherlandsIt is generally accepted that the effect of orthodontic tooth movement on the dental pulp in adolescents is reversible and that it has no long-lasting effect on pulpal physiology. However, it is not clear yet if the same conclusion is also valid for adult subjects. Thus, in two groups of rats, aged 6 and 40 weeks respectively, 3 molars at one side of the maxilla were moved together in a mesial direction with a standardized orthodontic appliance delivering a force of 10 cN. The contralateral side served as a control. Parasagittal histological sections were prepared after tooth movement for 1, 2, 4, 8, and 12 weeks. The pulp tissue was characterized for the different groups, with special emphasis on cell density, inflammatory cells, vascularity, and odontoblasts. Dimensions of dentin and the pulpal horns was determined and related with the duration of orthodontic force application and age ware evaluated. We found that neither in young nor in adult rats, force application led to long-lasting or irreversible changes in pulpal tissues. Dimensional variables showed significant age-related changes. In conclusion, orthodontic tooth movement per se has no long-lasting or irreversible effect on pulpal tissues, neither in the young nor in the adult animals.https://peerj.com/articles/1625.pdfDental pulpOrthodonticsWearAgeingRatsTooth movement |
| spellingShingle | Martina Von Böhl Yijin Ren Anne M. Kuijpers-Jagtman Piotr S. Fudalej Jaap C. Maltha Age-related changes of dental pulp tissue after experimental tooth movement in rats PeerJ Dental pulp Orthodontics Wear Ageing Rats Tooth movement |
| title | Age-related changes of dental pulp tissue after experimental tooth movement in rats |
| title_full | Age-related changes of dental pulp tissue after experimental tooth movement in rats |
| title_fullStr | Age-related changes of dental pulp tissue after experimental tooth movement in rats |
| title_full_unstemmed | Age-related changes of dental pulp tissue after experimental tooth movement in rats |
| title_short | Age-related changes of dental pulp tissue after experimental tooth movement in rats |
| title_sort | age related changes of dental pulp tissue after experimental tooth movement in rats |
| topic | Dental pulp Orthodontics Wear Ageing Rats Tooth movement |
| url | https://peerj.com/articles/1625.pdf |
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