SARS-CoV-2 IgG Antibody Seroprevalence in Children from the Amritsar District of Punjab
The majority of the children experience milder coronavirus disease 2019 (COVID-19) symptoms. Children represent a significant source of community transmission. Children under 18 years of age account for an estimated 4.8% of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections glob...
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| Format: | Article |
| Language: | English |
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The Korean Society for Clinical Laboratory Science
2022-09-01
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| Series: | Korean Journal of Clinical Laboratory Science |
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| Online Access: | http://www.kjcls.org/journal/view.html?doi=10.15324/kjcls.2022.54.3.173 |
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| author | Amandeep Kaur Narinder Singh Kanwardeep Singh Shailpreet Kaur Sidhu Harleen Kaur Poonam Jain Manmeet Kaur Mohan Jairath |
| author_facet | Amandeep Kaur Narinder Singh Kanwardeep Singh Shailpreet Kaur Sidhu Harleen Kaur Poonam Jain Manmeet Kaur Mohan Jairath |
| author_sort | Amandeep Kaur |
| collection | DOAJ |
| description | The majority of the children experience milder coronavirus disease 2019 (COVID-19) symptoms. Children represent a significant source of community transmission. Children under 18 years of age account for an estimated 4.8% of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections globally. However, no conclusive statements pertaining to the multi-fold aspects of the virus in children could be drawn due to the lower prevalence of pediatric cases. The present study was conducted to identify the indirect impact of SARS-CoV-2 infections on developing herd immunity among children in the age group 3 to 18 years by investigating their antibody levels. In the study, 240 children aged 3~18 years were recruited by the Department of Pediatrics, Government Medical College and Hospital, Amritsar, India, and quantification of the antibodies was performed at the Viral Research and Diagnostic Laboratory (VRDL), Government Medical College (GMC), Amritsar, India. Out of the 240 serum samples, 197 (82.08%) showed seropositivity, while 43 (17.92%) were seronegative. When stratified, it was observed that in the age group 3~6 years, 22.33% of children were found to have anti-SARS-CoV-2 antibodies while in the age groups 7~10 years, 11~14 years, and 15~18 years, respectively, 37.06%, 30.46%, and 10.15% were seropositive. Although there was seroconversion among children which was useful for predicting the next wave, no differences in seropositivity were observed between adults and children. |
| first_indexed | 2024-04-11T00:42:04Z |
| format | Article |
| id | doaj.art-04063b06c0e64af3abb982ce9f739871 |
| institution | Directory Open Access Journal |
| issn | 1738-3544 |
| language | English |
| last_indexed | 2024-04-11T00:42:04Z |
| publishDate | 2022-09-01 |
| publisher | The Korean Society for Clinical Laboratory Science |
| record_format | Article |
| series | Korean Journal of Clinical Laboratory Science |
| spelling | doaj.art-04063b06c0e64af3abb982ce9f7398712023-01-06T01:44:11ZengThe Korean Society for Clinical Laboratory ScienceKorean Journal of Clinical Laboratory Science1738-35442022-09-0154317317810.15324/kjcls.2022.54.3.173kjcls.2022.54.3.173SARS-CoV-2 IgG Antibody Seroprevalence in Children from the Amritsar District of PunjabAmandeep Kaur0Narinder Singh1Kanwardeep Singh2Shailpreet Kaur Sidhu3Harleen Kaur4Poonam Jain5Manmeet Kaur6Mohan Jairath7The Viral Research and Diagnostic Laboratory, Government Medical College, Amritsar, IndiaDepartment of Pediatrics, Government Medical College, Amritsar, IndiaDepartment of Microbiology, Government Medical College, Amritsar, IndiaDepartment of Microbiology, Government Medical College, Amritsar, IndiaThe Viral Research and Diagnostic Laboratory, Government Medical College, Amritsar, IndiaThe Viral Research and Diagnostic Laboratory, Government Medical College, Amritsar, IndiaDepartment of Pediatrics, Government Medical College, Amritsar, IndiaThe Viral Research and Diagnostic Laboratory, Government Medical College, Amritsar, IndiaThe majority of the children experience milder coronavirus disease 2019 (COVID-19) symptoms. Children represent a significant source of community transmission. Children under 18 years of age account for an estimated 4.8% of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections globally. However, no conclusive statements pertaining to the multi-fold aspects of the virus in children could be drawn due to the lower prevalence of pediatric cases. The present study was conducted to identify the indirect impact of SARS-CoV-2 infections on developing herd immunity among children in the age group 3 to 18 years by investigating their antibody levels. In the study, 240 children aged 3~18 years were recruited by the Department of Pediatrics, Government Medical College and Hospital, Amritsar, India, and quantification of the antibodies was performed at the Viral Research and Diagnostic Laboratory (VRDL), Government Medical College (GMC), Amritsar, India. Out of the 240 serum samples, 197 (82.08%) showed seropositivity, while 43 (17.92%) were seronegative. When stratified, it was observed that in the age group 3~6 years, 22.33% of children were found to have anti-SARS-CoV-2 antibodies while in the age groups 7~10 years, 11~14 years, and 15~18 years, respectively, 37.06%, 30.46%, and 10.15% were seropositive. Although there was seroconversion among children which was useful for predicting the next wave, no differences in seropositivity were observed between adults and children.http://www.kjcls.org/journal/view.html?doi=10.15324/kjcls.2022.54.3.173childelisaindiasars-cov-2 antibodiesseropositive |
| spellingShingle | Amandeep Kaur Narinder Singh Kanwardeep Singh Shailpreet Kaur Sidhu Harleen Kaur Poonam Jain Manmeet Kaur Mohan Jairath SARS-CoV-2 IgG Antibody Seroprevalence in Children from the Amritsar District of Punjab Korean Journal of Clinical Laboratory Science child elisa india sars-cov-2 antibodies seropositive |
| title | SARS-CoV-2 IgG Antibody Seroprevalence in Children from the Amritsar District of Punjab |
| title_full | SARS-CoV-2 IgG Antibody Seroprevalence in Children from the Amritsar District of Punjab |
| title_fullStr | SARS-CoV-2 IgG Antibody Seroprevalence in Children from the Amritsar District of Punjab |
| title_full_unstemmed | SARS-CoV-2 IgG Antibody Seroprevalence in Children from the Amritsar District of Punjab |
| title_short | SARS-CoV-2 IgG Antibody Seroprevalence in Children from the Amritsar District of Punjab |
| title_sort | sars cov 2 igg antibody seroprevalence in children from the amritsar district of punjab |
| topic | child elisa india sars-cov-2 antibodies seropositive |
| url | http://www.kjcls.org/journal/view.html?doi=10.15324/kjcls.2022.54.3.173 |
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