Six-minute walk distance predicts hospitalization in elderly peritoneal dialysis patients: a single-center prospective cohort study
Abstract Background The risk of adverse events associated with peritoneal dialysis (PD) in elderly patients has not been thoroughly investigated. The purpose of this study was to assess the association between physical function and hospitalization in elderly PD patients. Methods This is a single-cen...
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| Format: | Article |
| Language: | English |
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BMC
2021-06-01
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| Series: | Renal Replacement Therapy |
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| Online Access: | https://doi.org/10.1186/s41100-021-00354-8 |
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| author | Hiroki Yabe Yuto Imoto Ayaka Onoyama Sayaka Ito Kenichi Kono Yoshifumi Moriyama Keiko Okada Hirotake Kasuga Yasuhiko Ito |
| author_facet | Hiroki Yabe Yuto Imoto Ayaka Onoyama Sayaka Ito Kenichi Kono Yoshifumi Moriyama Keiko Okada Hirotake Kasuga Yasuhiko Ito |
| author_sort | Hiroki Yabe |
| collection | DOAJ |
| description | Abstract Background The risk of adverse events associated with peritoneal dialysis (PD) in elderly patients has not been thoroughly investigated. The purpose of this study was to assess the association between physical function and hospitalization in elderly PD patients. Methods This is a single-center prospective observational cohort study. Thirty-three aged patients (74.8 ± 5.9 years) participated in a 6-min walk distance, short physical performance battery (SPPB), lower extremity muscle strength, and 10-m walk speed. All subjects were followed until hospitalization to the end of the follow-up period. Results The 6-min walk distance was 332 ± 112.5 m; SPPB was 11 (8.3–12) points; the lower extremity muscle strength was 36.6 ± 9.6%; 10-m walk speed was 1.1± 0.2 m/s. During the follow-up, 19 patients (57.5%) were hospitalized. In the Kaplan-Meier survival analysis and log-rank test, a lower 6-min walk distance and PD vintage were significantly associated with hospitalization (p<0.05). After adjustment for PD vintage in Cox proportional analysis, the 6-min walk distance remained associated with hospitalization (95% confidence interval, 0.98–0.99). Conclusion Lower exercise tolerance assessed by the 6-min walk distance was significantly associated with hospitalization in elderly PD patients. Our findings indicate that measurement and intervention of exercise intolerance are essential to predict the clinical outcomes of elderly PD patients. Trial registration This study was prospectively registered at inception in the UMIN Clinical Trials Registry under identification number UMIN000038405 . |
| first_indexed | 2024-12-14T20:29:34Z |
| format | Article |
| id | doaj.art-04067450346045d8887594b62a1800bc |
| institution | Directory Open Access Journal |
| issn | 2059-1381 |
| language | English |
| last_indexed | 2024-12-14T20:29:34Z |
| publishDate | 2021-06-01 |
| publisher | BMC |
| record_format | Article |
| series | Renal Replacement Therapy |
| spelling | doaj.art-04067450346045d8887594b62a1800bc2022-12-21T22:48:33ZengBMCRenal Replacement Therapy2059-13812021-06-01711810.1186/s41100-021-00354-8Six-minute walk distance predicts hospitalization in elderly peritoneal dialysis patients: a single-center prospective cohort studyHiroki Yabe0Yuto Imoto1Ayaka Onoyama2Sayaka Ito3Kenichi Kono4Yoshifumi Moriyama5Keiko Okada6Hirotake Kasuga7Yasuhiko Ito8Department of Physical Therapy, School of Rehabilitation Sciences, Seirei Christopher UniversityDepartment of Rehabilitation, Nagoya Kyoritsu HospitalDepartment of Rehabilitation, Nagoya Kyoritsu HospitalDepartment of Rehabilitation, Nagoya Kyoritsu HospitalDepartment of Physical Therapy, School of Health Sciences at Narita, International University of Health and WelfareDepartment of Wellness Center, Nagoya Kyoritsu HospitalDepartment of Nephrology, Nagoya Kyoritsu HospitalDepartment of Nephrology, Nagoya Kyoritsu HospitalDepartment of Nephrology and Rheumatology, Aichi Medical UniversityAbstract Background The risk of adverse events associated with peritoneal dialysis (PD) in elderly patients has not been thoroughly investigated. The purpose of this study was to assess the association between physical function and hospitalization in elderly PD patients. Methods This is a single-center prospective observational cohort study. Thirty-three aged patients (74.8 ± 5.9 years) participated in a 6-min walk distance, short physical performance battery (SPPB), lower extremity muscle strength, and 10-m walk speed. All subjects were followed until hospitalization to the end of the follow-up period. Results The 6-min walk distance was 332 ± 112.5 m; SPPB was 11 (8.3–12) points; the lower extremity muscle strength was 36.6 ± 9.6%; 10-m walk speed was 1.1± 0.2 m/s. During the follow-up, 19 patients (57.5%) were hospitalized. In the Kaplan-Meier survival analysis and log-rank test, a lower 6-min walk distance and PD vintage were significantly associated with hospitalization (p<0.05). After adjustment for PD vintage in Cox proportional analysis, the 6-min walk distance remained associated with hospitalization (95% confidence interval, 0.98–0.99). Conclusion Lower exercise tolerance assessed by the 6-min walk distance was significantly associated with hospitalization in elderly PD patients. Our findings indicate that measurement and intervention of exercise intolerance are essential to predict the clinical outcomes of elderly PD patients. Trial registration This study was prospectively registered at inception in the UMIN Clinical Trials Registry under identification number UMIN000038405 .https://doi.org/10.1186/s41100-021-00354-8Six-minute walk distancePeritoneal dialysisElderly patientsHospitalization |
| spellingShingle | Hiroki Yabe Yuto Imoto Ayaka Onoyama Sayaka Ito Kenichi Kono Yoshifumi Moriyama Keiko Okada Hirotake Kasuga Yasuhiko Ito Six-minute walk distance predicts hospitalization in elderly peritoneal dialysis patients: a single-center prospective cohort study Renal Replacement Therapy Six-minute walk distance Peritoneal dialysis Elderly patients Hospitalization |
| title | Six-minute walk distance predicts hospitalization in elderly peritoneal dialysis patients: a single-center prospective cohort study |
| title_full | Six-minute walk distance predicts hospitalization in elderly peritoneal dialysis patients: a single-center prospective cohort study |
| title_fullStr | Six-minute walk distance predicts hospitalization in elderly peritoneal dialysis patients: a single-center prospective cohort study |
| title_full_unstemmed | Six-minute walk distance predicts hospitalization in elderly peritoneal dialysis patients: a single-center prospective cohort study |
| title_short | Six-minute walk distance predicts hospitalization in elderly peritoneal dialysis patients: a single-center prospective cohort study |
| title_sort | six minute walk distance predicts hospitalization in elderly peritoneal dialysis patients a single center prospective cohort study |
| topic | Six-minute walk distance Peritoneal dialysis Elderly patients Hospitalization |
| url | https://doi.org/10.1186/s41100-021-00354-8 |
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