Turicibacter fermentation enhances the inhibitory effects of Antrodia camphorata supplementation on tumorigenic serotonin and Wnt pathways and promotes ROS-mediated apoptosis of Caco-2 cells

Turicibacter fermentation enhances the inhibitory effects of Antrodia camphorata supplementation on tumorigenic serotonin and Wnt pathways and promotes ROS-mediated apoptosis of Caco-2 cells

Introduction: Diet-induced obesity has been shown to decrease the abundance of Turicibacter, a genus known to play a role in the serotonin signaling system, which is associated with colorectal tumorigenesis, making the presence of Turicibacter potentially influential in the protection of intestinal...

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Bibliographic Details
Main Authors: Ting-Chun Lin, Anand Soorneedi, Yingxue Guan, Ying Tang, Eleanor Shi, Matthew D. Moore, Zhenhua Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-08-01
Series:Frontiers in Pharmacology
Subjects:
mushroom polysaccharide
microbiome
Turicibacter
serotonin
Wnt/βcatenin signaling
reactive oxygen species
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1203087/full

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