Chronic N-methyl-d-aspartate administration increases the turnover of arachidonic acid within brain phospholipids of the unanesthetized rat

Chronic N-methyl-d-aspartate administration increases the turnover of arachidonic acid within brain phospholipids of the unanesthetized rat

Whereas antibipolar drug administration to rats reduces brain arachidonic acid turnover, excessive N-methyl-d-aspartate (NMDA) signaling is thought to contribute to bipolar disorder symptoms and may increase arachidonic acid turnover in rat brain phospholipids. To determine whether chronic NMDA woul...

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Bibliographic Details
Main Authors: Ho-Joo Lee, Jagadeesh S. Rao, Lisa Chang, Stanley I. Rapoport, Richard P. Bazinet
Format: Article
Language:English
Published: Elsevier 2008-01-01
Series:Journal of Lipid Research
Subjects:
bipolar disorder
signaling
neuroreceptor
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520428913

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http://www.sciencedirect.com/science/article/pii/S0022227520428913

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