New capabilities of laboratory diagnosis of thromboses
The growing number of thromboses has been observed in various fields of medicine, which makes the issues of early diagnosis andinvestigation of thrombotic condition predictors more topical.Evaluation of hemostasis and investigation of risk factors of boththrombotic and hemorrhagic states is one of t...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Research Center of Neurology
2017-02-01
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| Series: | Анналы клинической и экспериментальной неврологии |
| Subjects: | |
| Online Access: | https://annaly-nevrologii.com/journal/pathID/article/viewFile/136/142 |
| Summary: | The growing number of thromboses has been observed in various fields of medicine, which makes the issues of early diagnosis andinvestigation of thrombotic condition predictors more topical.Evaluation of hemostasis and investigation of risk factors of boththrombotic and hemorrhagic states is one of the most complexdiagnostic problems. The objectives of laboratory diagnosis includenot only studying of already known indicators of thrombovascularhemostasis and standard coagulation tests but alsodeveloping, automating, and improving of new methods for detectionof biomarkers of hemostasis disturbances. According tothe results of modern research, a high level of the subpopulationof procoagulant or coated platelets, known as COAT-platelets, inpatient blood can be considered as this new marker for predictingthrombosis. COAT-platelets are a subpopulation of collagen andthrombin-activated platelets maintaining a high procoagulantactivity of blood. |
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| ISSN: | 2075-5473 2409-2533 |