New capabilities of laboratory diagnosis of thromboses

The growing number of thromboses has been observed in various fields of medicine, which makes the issues of early diagnosis andinvestigation of thrombotic condition predictors more topical.Evaluation of hemostasis and investigation of risk factors of boththrombotic and hemorrhagic states is one of t...

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Main Authors: A. A. Shabalina, M. V. Kostyreva, M. M. Tanashyan
Format: Article
Language:English
Published: Research Center of Neurology 2017-02-01
Series:Анналы клинической и экспериментальной неврологии
Subjects:
Online Access:https://annaly-nevrologii.com/journal/pathID/article/viewFile/136/142
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author A. A. Shabalina
M. V. Kostyreva
M. M. Tanashyan
author_facet A. A. Shabalina
M. V. Kostyreva
M. M. Tanashyan
author_sort A. A. Shabalina
collection DOAJ
description The growing number of thromboses has been observed in various fields of medicine, which makes the issues of early diagnosis andinvestigation of thrombotic condition predictors more topical.Evaluation of hemostasis and investigation of risk factors of boththrombotic and hemorrhagic states is one of the most complexdiagnostic problems. The objectives of laboratory diagnosis includenot only studying of already known indicators of thrombovascularhemostasis and standard coagulation tests but alsodeveloping, automating, and improving of new methods for detectionof biomarkers of hemostasis disturbances. According tothe results of modern research, a high level of the subpopulationof procoagulant or coated platelets, known as COAT-platelets, inpatient blood can be considered as this new marker for predictingthrombosis. COAT-platelets are a subpopulation of collagen andthrombin-activated platelets maintaining a high procoagulantactivity of blood.
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spelling doaj.art-0407ec3479024e1e8f4233b495205a712022-12-22T02:36:12ZengResearch Center of NeurologyАнналы клинической и экспериментальной неврологии2075-54732409-25332017-02-0193566010.17816/psaic13662New capabilities of laboratory diagnosis of thrombosesA. A. Shabalina0M. V. Kostyreva1M. M. Tanashyan2Research Center of Neurology (Moscow)Research Center of Neurology (Moscow)Research Center of Neurology (Moscow)The growing number of thromboses has been observed in various fields of medicine, which makes the issues of early diagnosis andinvestigation of thrombotic condition predictors more topical.Evaluation of hemostasis and investigation of risk factors of boththrombotic and hemorrhagic states is one of the most complexdiagnostic problems. The objectives of laboratory diagnosis includenot only studying of already known indicators of thrombovascularhemostasis and standard coagulation tests but alsodeveloping, automating, and improving of new methods for detectionof biomarkers of hemostasis disturbances. According tothe results of modern research, a high level of the subpopulationof procoagulant or coated platelets, known as COAT-platelets, inpatient blood can be considered as this new marker for predictingthrombosis. COAT-platelets are a subpopulation of collagen andthrombin-activated platelets maintaining a high procoagulantactivity of blood.https://annaly-nevrologii.com/journal/pathID/article/viewFile/136/142coat-plateletshypercoagulationthrombosispredictor of thrombosis
spellingShingle A. A. Shabalina
M. V. Kostyreva
M. M. Tanashyan
New capabilities of laboratory diagnosis of thromboses
Анналы клинической и экспериментальной неврологии
coat-platelets
hypercoagulation
thrombosis
predictor of thrombosis
title New capabilities of laboratory diagnosis of thromboses
title_full New capabilities of laboratory diagnosis of thromboses
title_fullStr New capabilities of laboratory diagnosis of thromboses
title_full_unstemmed New capabilities of laboratory diagnosis of thromboses
title_short New capabilities of laboratory diagnosis of thromboses
title_sort new capabilities of laboratory diagnosis of thromboses
topic coat-platelets
hypercoagulation
thrombosis
predictor of thrombosis
url https://annaly-nevrologii.com/journal/pathID/article/viewFile/136/142
work_keys_str_mv AT aashabalina newcapabilitiesoflaboratorydiagnosisofthromboses
AT mvkostyreva newcapabilitiesoflaboratorydiagnosisofthromboses
AT mmtanashyan newcapabilitiesoflaboratorydiagnosisofthromboses