Insomnia is common in inflammatory bowel disease (IBD) and is associated with mental health conditions as well as IBD activity
Background/Aims Insomnia is common in people with chronic medical conditions, such as inflammatory bowel disease (IBD), and is readily treatable through cognitive behavioral therapy for insomnia. This study aimed to describe the associations with insomnia in people with IBD and its relationship to I...
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| Format: | Article |
| Language: | English |
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Korean Association for the Study of Intestinal Diseases
2024-01-01
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| Series: | Intestinal Research |
| Subjects: | |
| Online Access: | http://irjournal.org/upload/pdf/ir-2023-00028.pdf |
| _version_ | 1797323649124925440 |
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| author | Alex Barnes Jane M Andrews Sutapa Mukherjee Robert V Bryant Peter Bampton Robert J. Fraser Réme Mountifield |
| author_facet | Alex Barnes Jane M Andrews Sutapa Mukherjee Robert V Bryant Peter Bampton Robert J. Fraser Réme Mountifield |
| author_sort | Alex Barnes |
| collection | DOAJ |
| description | Background/Aims Insomnia is common in people with chronic medical conditions, such as inflammatory bowel disease (IBD), and is readily treatable through cognitive behavioral therapy for insomnia. This study aimed to describe the associations with insomnia in people with IBD and its relationship to IBD-related disability. Methods An online questionnaire was administered through 3 tertiary IBD centers, social media, and Crohn’s Colitis Australia. The questionnaire included the Insomnia Severity Index (ISI), a validated assessment of insomnia. Measures of anxiety, depression, physical activity, and disability were also included. IBD activity was assessed using validated patient reported scores. A multivariate model was constructed for clinically significant insomnia and ISI scores. Subpopulations of Crohn’s disease and ulcerative colitis were considered. Results In a cohort of 670 respondents the median age was 41 years (range, 32–70 years), with the majority female (78.4%), the majority had Crohn’s disease (57.3%). Increasingly severe disability was associated with worse insomnia score. Clinically significant insomnia was associated with clinically active IBD, abdominal pain, anxiety, and depression, in a multivariate model. In an ulcerative colitis population, Simple Clinical Colitis Activity Index components of general well-being and urgency were associated with worse ISI score in a model including depression and anxiety. In those with Crohn’s disease, the multivariate model included Harvey Bradshaw Index score in addition to depression and anxiety. Conclusions Insomnia is common in people with IBD and is associated with increased disability. Abdominal pain and mental health conditions should prompt consideration for screening for insomnia and referral for cognitive behavioral therapy for insomnia. |
| first_indexed | 2024-03-08T05:31:38Z |
| format | Article |
| id | doaj.art-040862a6a5ba44f2a7cb67def59e5eea |
| institution | Directory Open Access Journal |
| issn | 1598-9100 2288-1956 |
| language | English |
| last_indexed | 2024-03-08T05:31:38Z |
| publishDate | 2024-01-01 |
| publisher | Korean Association for the Study of Intestinal Diseases |
| record_format | Article |
| series | Intestinal Research |
| spelling | doaj.art-040862a6a5ba44f2a7cb67def59e5eea2024-02-06T04:27:30ZengKorean Association for the Study of Intestinal DiseasesIntestinal Research1598-91002288-19562024-01-0122110411410.5217/ir.2023.000281027Insomnia is common in inflammatory bowel disease (IBD) and is associated with mental health conditions as well as IBD activityAlex Barnes0Jane M Andrews1Sutapa Mukherjee2Robert V Bryant3Peter Bampton4Robert J. Fraser5Réme Mountifield6 Department of Gastroenterology, Southern Adelaide Local Health Network (SALHN) Flinders Medical Centre, Bedford Park, Australia Inflammatory Bowel Disease Service, Department of Gastroenterology and Hepatology, Central Adelaide Local Health Network (CALHN) Royal Adelaide Hospital, Adelaide, Australia Adelaide Institute for Sleep Health, Flinders Health and Medical Research Institute, College of Medicine and Public Health, Flinders University, Bedford Park, Australia School of Medicine, Faculty of Health & Medical Sciences, University of Adelaide, Adelaide, Australia Adelaide Institute for Sleep Health, Flinders Health and Medical Research Institute, College of Medicine and Public Health, Flinders University, Bedford Park, Australia Department of Gastroenterology, Southern Adelaide Local Health Network (SALHN) Flinders Medical Centre, Bedford Park, Australia Department of Gastroenterology, Southern Adelaide Local Health Network (SALHN) Flinders Medical Centre, Bedford Park, AustraliaBackground/Aims Insomnia is common in people with chronic medical conditions, such as inflammatory bowel disease (IBD), and is readily treatable through cognitive behavioral therapy for insomnia. This study aimed to describe the associations with insomnia in people with IBD and its relationship to IBD-related disability. Methods An online questionnaire was administered through 3 tertiary IBD centers, social media, and Crohn’s Colitis Australia. The questionnaire included the Insomnia Severity Index (ISI), a validated assessment of insomnia. Measures of anxiety, depression, physical activity, and disability were also included. IBD activity was assessed using validated patient reported scores. A multivariate model was constructed for clinically significant insomnia and ISI scores. Subpopulations of Crohn’s disease and ulcerative colitis were considered. Results In a cohort of 670 respondents the median age was 41 years (range, 32–70 years), with the majority female (78.4%), the majority had Crohn’s disease (57.3%). Increasingly severe disability was associated with worse insomnia score. Clinically significant insomnia was associated with clinically active IBD, abdominal pain, anxiety, and depression, in a multivariate model. In an ulcerative colitis population, Simple Clinical Colitis Activity Index components of general well-being and urgency were associated with worse ISI score in a model including depression and anxiety. In those with Crohn’s disease, the multivariate model included Harvey Bradshaw Index score in addition to depression and anxiety. Conclusions Insomnia is common in people with IBD and is associated with increased disability. Abdominal pain and mental health conditions should prompt consideration for screening for insomnia and referral for cognitive behavioral therapy for insomnia.http://irjournal.org/upload/pdf/ir-2023-00028.pdfinflammatory bowel diseasesleep initiation and maintenance disordersanalgesics, opioidquality of life |
| spellingShingle | Alex Barnes Jane M Andrews Sutapa Mukherjee Robert V Bryant Peter Bampton Robert J. Fraser Réme Mountifield Insomnia is common in inflammatory bowel disease (IBD) and is associated with mental health conditions as well as IBD activity Intestinal Research inflammatory bowel disease sleep initiation and maintenance disorders analgesics, opioid quality of life |
| title | Insomnia is common in inflammatory bowel disease (IBD) and is associated with mental health conditions as well as IBD activity |
| title_full | Insomnia is common in inflammatory bowel disease (IBD) and is associated with mental health conditions as well as IBD activity |
| title_fullStr | Insomnia is common in inflammatory bowel disease (IBD) and is associated with mental health conditions as well as IBD activity |
| title_full_unstemmed | Insomnia is common in inflammatory bowel disease (IBD) and is associated with mental health conditions as well as IBD activity |
| title_short | Insomnia is common in inflammatory bowel disease (IBD) and is associated with mental health conditions as well as IBD activity |
| title_sort | insomnia is common in inflammatory bowel disease ibd and is associated with mental health conditions as well as ibd activity |
| topic | inflammatory bowel disease sleep initiation and maintenance disorders analgesics, opioid quality of life |
| url | http://irjournal.org/upload/pdf/ir-2023-00028.pdf |
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