Discovery of Hepatotoxic Equivalent Markers and Mechanism of <i>Polygonum multiflorum</i> Thunb. by Metabolomics Coupled with Molecular Docking

Discovery of Hepatotoxic Equivalent Markers and Mechanism of <i>Polygonum multiflorum</i> Thunb. by Metabolomics Coupled with Molecular Docking

<i>Polygonum multiflorum Thunb</i>. (PMT), a commonly used Chinese herbal medicine for treating diseases such as poisoning and white hair, has attracted constant attention due to the frequent occurrence of liver injury incidents. To date, its hepatotoxic equivalent markers (HEMs) and pot...

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Bibliographic Details
Main Authors: Yinhuan Zhang, Lirong Liu, Menghan Feng, Hao Wu, Yihang Dai, Zhixin Jia, Cong Fang, Mingyan Liu, Xiaoning Yan, Meixia Zhu, Beibei Huang, Biqiong Qu, Hongbin Xiao
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Molecules
Subjects:
<i>Polygonum multiflorum</i> Thunb.
hepatotoxic equivalent markers
liver injury
metabolomics
hepatotoxic mechanism
Online Access:https://www.mdpi.com/1420-3049/28/1/25

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