LOXL2 in Cancer: A Two-Decade Perspective
Lysyl Oxidase Like 2 (LOXL2) belongs to the lysyl oxidase (LOX) family, which comprises five lysine tyrosylquinone (LTQ)-dependent copper amine oxidases in humans. In 2003, LOXL2 was first identified as a promoter of tumour progression and, over the course of two decades, numerous studies have firml...
Main Authors: | Amparo Cano, Pilar Eraso, María J. Mazón, Francisco Portillo |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2023-09-01
|
Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/24/18/14405 |
Similar Items
-
New Functions of Intracellular LOXL2: Modulation of RNA-Binding Proteins
by: Pilar Eraso, et al.
Published: (2023-05-01) -
Loxl2 and Loxl3 Paralogues Play Redundant Roles during Mouse Development
by: Patricia G. Santamaría, et al.
Published: (2022-05-01) -
Loxl3 Promotes Melanoma Progression and Dissemination Influencing Cell Plasticity and Survival
by: Alberto Vázquez-Naharro, et al.
Published: (2022-02-01) -
LOXL2 catalytically inactive mutants mediate epithelial-to-mesenchymal transition
by: Eva P. Cuevas, et al.
Published: (2014-01-01) -
Multiple Roles of LOXL2 in the Progression of Hepatocellular Carcinoma and Its Potential for Therapeutic Targeting
by: Jelena Radić, et al.
Published: (2023-07-01)