UK consensus definitions for necrotising otitis externa: a Delphi study

Objective To establish consensus definitions for necrotising otitis externa (NOE) to facilitate the diagnosis and exclusion of NOE in clinical practice and expedite future high-quality study of this neglected condition.Design The work comprised of a systematic review of the literature, five iterativ...

Full description

Bibliographic Details
Main Authors: Emma Stapleton, O Martin Williams, Pieter Pretorius, Monique I Andersson, Maia Patrick-Smith, Susanne H Hodgson, Maha M Khan, Pablo Martinez-Devesa, Martin McNally
Format: Article
Language:English
Published: BMJ Publishing Group 2023-02-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/13/2/e061349.full
_version_ 1797901010371346432
author Emma Stapleton
O Martin Williams
Pieter Pretorius
Monique I Andersson
Maia Patrick-Smith
Susanne H Hodgson
Maha M Khan
Pablo Martinez-Devesa
Martin McNally
author_facet Emma Stapleton
O Martin Williams
Pieter Pretorius
Monique I Andersson
Maia Patrick-Smith
Susanne H Hodgson
Maha M Khan
Pablo Martinez-Devesa
Martin McNally
author_sort Emma Stapleton
collection DOAJ
description Objective To establish consensus definitions for necrotising otitis externa (NOE) to facilitate the diagnosis and exclusion of NOE in clinical practice and expedite future high-quality study of this neglected condition.Design The work comprised of a systematic review of the literature, five iterative rounds of consultation via a Delphi process and open discussion within the collaborative. An expert panel analysed the results to produce the final outputs which were shared with and endorsed by national specialty bodies.Setting Secondary care in the UK.Participants UK clinical specialists practising in infection, ear nose and throat (ENT) surgery or radiology.Main outcome measures Definitions and statements meeting the following criteria were accepted: (a) minimum of 70% of respondents in agreement or strong agreement with a definition/statement AND (b) <15% of respondents in disagreement or strong disagreement with a definition/statement.Results Seventy-four UK clinicians specialising in ENT, Infection and Radiology with a special interest in NOE took part in the work which was undertaken between 2019 and 2021. The minimum response rate for a Round was 76%. Consensus criteria for all proposed case definitions, outcome definitions and consensus statements were met in the fifth round.Conclusions This work distills the clinical opinion of a large group of multidisciplinary specialists from across the UK to create practical definitions and statements to support clinical practice and research for NOE. This is the first step in an iterative process. Further work will seek to validate and test these definitions and inform their evolution.
first_indexed 2024-04-10T08:55:10Z
format Article
id doaj.art-041380faa838449dbf742824c998ea0f
institution Directory Open Access Journal
issn 2044-6055
language English
last_indexed 2024-04-10T08:55:10Z
publishDate 2023-02-01
publisher BMJ Publishing Group
record_format Article
series BMJ Open
spelling doaj.art-041380faa838449dbf742824c998ea0f2023-02-21T16:00:12ZengBMJ Publishing GroupBMJ Open2044-60552023-02-0113210.1136/bmjopen-2022-061349UK consensus definitions for necrotising otitis externa: a Delphi studyEmma Stapleton0O Martin Williams1Pieter Pretorius2Monique I Andersson3Maia Patrick-Smith4Susanne H Hodgson5Maha M Khan6Pablo Martinez-Devesa7Martin McNally8Department of Otolaryngology, Central Manchester University Hospitals NHS Foundation Trust, Manchester, Greater Manchester, UKDepartment of Microbiology, University Hospitals Bristol and Weston NHS Foundation Trust, Bristol, UKDepartment of Neuroradiology, John Radcliffe Hospital, Oxford, UKDepartment of Microbiology, Oxford University Hospitals NHS Foundation Trust, Oxford, Oxfordshire, UKUniversity of Oxford, Oxford, Oxfordshire, UKDepartment of Microbiology, Oxford University Hospitals NHS Foundation Trust, Oxford, Oxfordshire, UKCentral Manchester University Hospitals NHS Foundation Trust, Manchester, Greater Manchester, UKDepartment of ENT, John Radcliffe Hospital, Oxford, UKNuffield Orthopaedic centre, Oxford University Hospitals NHS Foundation Trust Nuffield Orthopaedic Centre, Oxford, Oxfordshire, UKObjective To establish consensus definitions for necrotising otitis externa (NOE) to facilitate the diagnosis and exclusion of NOE in clinical practice and expedite future high-quality study of this neglected condition.Design The work comprised of a systematic review of the literature, five iterative rounds of consultation via a Delphi process and open discussion within the collaborative. An expert panel analysed the results to produce the final outputs which were shared with and endorsed by national specialty bodies.Setting Secondary care in the UK.Participants UK clinical specialists practising in infection, ear nose and throat (ENT) surgery or radiology.Main outcome measures Definitions and statements meeting the following criteria were accepted: (a) minimum of 70% of respondents in agreement or strong agreement with a definition/statement AND (b) <15% of respondents in disagreement or strong disagreement with a definition/statement.Results Seventy-four UK clinicians specialising in ENT, Infection and Radiology with a special interest in NOE took part in the work which was undertaken between 2019 and 2021. The minimum response rate for a Round was 76%. Consensus criteria for all proposed case definitions, outcome definitions and consensus statements were met in the fifth round.Conclusions This work distills the clinical opinion of a large group of multidisciplinary specialists from across the UK to create practical definitions and statements to support clinical practice and research for NOE. This is the first step in an iterative process. Further work will seek to validate and test these definitions and inform their evolution.https://bmjopen.bmj.com/content/13/2/e061349.full
spellingShingle Emma Stapleton
O Martin Williams
Pieter Pretorius
Monique I Andersson
Maia Patrick-Smith
Susanne H Hodgson
Maha M Khan
Pablo Martinez-Devesa
Martin McNally
UK consensus definitions for necrotising otitis externa: a Delphi study
BMJ Open
title UK consensus definitions for necrotising otitis externa: a Delphi study
title_full UK consensus definitions for necrotising otitis externa: a Delphi study
title_fullStr UK consensus definitions for necrotising otitis externa: a Delphi study
title_full_unstemmed UK consensus definitions for necrotising otitis externa: a Delphi study
title_short UK consensus definitions for necrotising otitis externa: a Delphi study
title_sort uk consensus definitions for necrotising otitis externa a delphi study
url https://bmjopen.bmj.com/content/13/2/e061349.full
work_keys_str_mv AT emmastapleton ukconsensusdefinitionsfornecrotisingotitisexternaadelphistudy
AT omartinwilliams ukconsensusdefinitionsfornecrotisingotitisexternaadelphistudy
AT pieterpretorius ukconsensusdefinitionsfornecrotisingotitisexternaadelphistudy
AT moniqueiandersson ukconsensusdefinitionsfornecrotisingotitisexternaadelphistudy
AT maiapatricksmith ukconsensusdefinitionsfornecrotisingotitisexternaadelphistudy
AT susannehhodgson ukconsensusdefinitionsfornecrotisingotitisexternaadelphistudy
AT mahamkhan ukconsensusdefinitionsfornecrotisingotitisexternaadelphistudy
AT pablomartinezdevesa ukconsensusdefinitionsfornecrotisingotitisexternaadelphistudy
AT martinmcnally ukconsensusdefinitionsfornecrotisingotitisexternaadelphistudy