The Prevalence of Cardiovascular Disease Risk Factors and the Framingham Risk Score in Patients Undergoing Percutaneous Intervention Over the Last 17 Years by Gender: Time-trend Analysis From the Mayo Clinic PCI Registry
Objectives: This study aims to investigate trends of cardiovascular disease (CVD) risk factor profiles over 17 years in percutaneous coronary intervention (PCI) patients at the Mayo Clinic. Methods: We performed a time-trend analysis within the Mayo Clinic PCI Registry from 1994 to 2010. Results wer...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Korean Society for Preventive Medicine
2014-07-01
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| Series: | Journal of Preventive Medicine and Public Health |
| Subjects: | |
| Online Access: | http://www.jpmph.org/upload/pdf/jpmph-47-4-216.pdf |
| _version_ | 1811254279591165952 |
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| author | Moo-Sik Lee Andreas J. Flammer Hyun-Soo Kim Jee-Young Hong Jing Li Ryan J. Lennon Amir Lerman |
| author_facet | Moo-Sik Lee Andreas J. Flammer Hyun-Soo Kim Jee-Young Hong Jing Li Ryan J. Lennon Amir Lerman |
| author_sort | Moo-Sik Lee |
| collection | DOAJ |
| description | Objectives: This study aims to investigate trends of cardiovascular disease (CVD) risk factor profiles over 17 years in percutaneous coronary intervention (PCI) patients at the Mayo Clinic. Methods: We performed a time-trend analysis within the Mayo Clinic PCI Registry from 1994 to 2010. Results were the incidence and prevalence of CVD risk factors as estimate by the Framingham risk score. Results: Between 1994 and 2010, 25 519 patients underwent a PCI. During the time assessed, the mean age at PCI became older, but the gender distribution did not change. A significant trend towards higher body mass index and more prevalent hypercholesterolemia, hypertension, and diabetes was found over time. The prevalence of current smokers remained unchanged. The prevalence of ever-smokers decreased among males, but increased among females. However, overall CVD risk according to the Framingham risk score (FRS) and 10-year CVD risk significantly decreased. The use of most of medications elevated from 1994 to 2010, except for β-blockers and angiotensin converting enzyme inhibitors decreased after 2007 and 2006 in both baseline and discharge, respectively. Conclusions: Most of the major risk factors improved and the FRS and 10-year CVD risk declined in this population of PCI patients. However, obesity, history of hypercholesterolemia, hypertension, diabetes, and medication use increased substantially. Improvements to blood pressure and lipid profile management because of medication use may have influenced the positive trends. |
| first_indexed | 2024-04-12T17:03:57Z |
| format | Article |
| id | doaj.art-041490d4624347aea4e3cea68935aee5 |
| institution | Directory Open Access Journal |
| issn | 1975-8375 2233-4521 |
| language | English |
| last_indexed | 2024-04-12T17:03:57Z |
| publishDate | 2014-07-01 |
| publisher | Korean Society for Preventive Medicine |
| record_format | Article |
| series | Journal of Preventive Medicine and Public Health |
| spelling | doaj.art-041490d4624347aea4e3cea68935aee52022-12-22T03:23:59ZengKorean Society for Preventive MedicineJournal of Preventive Medicine and Public Health1975-83752233-45212014-07-0147421622910.3961/jpmph.2014.47.4.2161790The Prevalence of Cardiovascular Disease Risk Factors and the Framingham Risk Score in Patients Undergoing Percutaneous Intervention Over the Last 17 Years by Gender: Time-trend Analysis From the Mayo Clinic PCI RegistryMoo-Sik Lee0Andreas J. Flammer1Hyun-Soo Kim2Jee-Young Hong3Jing Li4Ryan J. Lennon5Amir Lerman6 Department of Preventive Medicine, Konyang University College of Medicine, Daejeon, Korea Division of Cardiovascular Diseases, Department of Medicine, Mayo Clinic, Rochester, MN, USA Department of Preventive Medicine, Konyang University College of Medicine, Daejeon, Korea Department of Preventive Medicine, Konyang University College of Medicine, Daejeon, Korea Division of Cardiovascular Diseases, Department of Medicine, Mayo Clinic, Rochester, MN, USA Division of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, MN, USA Division of Cardiovascular Diseases, Department of Medicine, Mayo Clinic, Rochester, MN, USAObjectives: This study aims to investigate trends of cardiovascular disease (CVD) risk factor profiles over 17 years in percutaneous coronary intervention (PCI) patients at the Mayo Clinic. Methods: We performed a time-trend analysis within the Mayo Clinic PCI Registry from 1994 to 2010. Results were the incidence and prevalence of CVD risk factors as estimate by the Framingham risk score. Results: Between 1994 and 2010, 25 519 patients underwent a PCI. During the time assessed, the mean age at PCI became older, but the gender distribution did not change. A significant trend towards higher body mass index and more prevalent hypercholesterolemia, hypertension, and diabetes was found over time. The prevalence of current smokers remained unchanged. The prevalence of ever-smokers decreased among males, but increased among females. However, overall CVD risk according to the Framingham risk score (FRS) and 10-year CVD risk significantly decreased. The use of most of medications elevated from 1994 to 2010, except for β-blockers and angiotensin converting enzyme inhibitors decreased after 2007 and 2006 in both baseline and discharge, respectively. Conclusions: Most of the major risk factors improved and the FRS and 10-year CVD risk declined in this population of PCI patients. However, obesity, history of hypercholesterolemia, hypertension, diabetes, and medication use increased substantially. Improvements to blood pressure and lipid profile management because of medication use may have influenced the positive trends.http://www.jpmph.org/upload/pdf/jpmph-47-4-216.pdfCardiovascular diseasesPercutaneous coronary interventionTrendsRisk factors |
| spellingShingle | Moo-Sik Lee Andreas J. Flammer Hyun-Soo Kim Jee-Young Hong Jing Li Ryan J. Lennon Amir Lerman The Prevalence of Cardiovascular Disease Risk Factors and the Framingham Risk Score in Patients Undergoing Percutaneous Intervention Over the Last 17 Years by Gender: Time-trend Analysis From the Mayo Clinic PCI Registry Journal of Preventive Medicine and Public Health Cardiovascular diseases Percutaneous coronary intervention Trends Risk factors |
| title | The Prevalence of Cardiovascular Disease Risk Factors and the Framingham Risk Score in Patients Undergoing Percutaneous Intervention Over the Last 17 Years by Gender: Time-trend Analysis From the Mayo Clinic PCI Registry |
| title_full | The Prevalence of Cardiovascular Disease Risk Factors and the Framingham Risk Score in Patients Undergoing Percutaneous Intervention Over the Last 17 Years by Gender: Time-trend Analysis From the Mayo Clinic PCI Registry |
| title_fullStr | The Prevalence of Cardiovascular Disease Risk Factors and the Framingham Risk Score in Patients Undergoing Percutaneous Intervention Over the Last 17 Years by Gender: Time-trend Analysis From the Mayo Clinic PCI Registry |
| title_full_unstemmed | The Prevalence of Cardiovascular Disease Risk Factors and the Framingham Risk Score in Patients Undergoing Percutaneous Intervention Over the Last 17 Years by Gender: Time-trend Analysis From the Mayo Clinic PCI Registry |
| title_short | The Prevalence of Cardiovascular Disease Risk Factors and the Framingham Risk Score in Patients Undergoing Percutaneous Intervention Over the Last 17 Years by Gender: Time-trend Analysis From the Mayo Clinic PCI Registry |
| title_sort | prevalence of cardiovascular disease risk factors and the framingham risk score in patients undergoing percutaneous intervention over the last 17 years by gender time trend analysis from the mayo clinic pci registry |
| topic | Cardiovascular diseases Percutaneous coronary intervention Trends Risk factors |
| url | http://www.jpmph.org/upload/pdf/jpmph-47-4-216.pdf |
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