Development of a glycoproteomic strategy to detect more aggressive prostate cancer using lectin-immunoassays for serum fucosylated PSA

Development of a glycoproteomic strategy to detect more aggressive prostate cancer using lectin-immunoassays for serum fucosylated PSA

Abstract Background Prostate-specific antigen (PSA) is commonly used as a serum biomarker for the detection of prostate cancer. However, levels of PSA in serum do not reliably distinguish aggressive prostate cancer from non-aggressive disease. Therefore, there is an urgent need for biomarkers that c...

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Bibliographic Details
Main Authors: Ce Wang, Naseruddin Höti, Tung-Shing Mamie Lih, Lori J. Sokoll, Rui Zhang, Zhen Zhang, Hui Zhang, Daniel W. Chan
Format: Article
Language:English
Published: BMC 2019-04-01
Series:Clinical Proteomics
Subjects:
Lectin-immunoassays
Glycoproteomic
Fucosylated PSA
Prostate cancer
Online Access:http://link.springer.com/article/10.1186/s12014-019-9234-4

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