Pulmonary tuberculosis incidence and drug resistance-related factors analysis in North China

Background: This study analysis the epidemiological characteristics of incidence, gender, age, occupation, educational level, income, residence location, and timescale of 773 pulmonary tuberculosis patients in Hulin County in North China from 2014 to 2016. Methods: Two hundred and sixty-seven strain...

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Main Authors: Zheng Qi, Wei Yang, Yan-Fu Wang, Chang Liu
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2019-01-01
Series:Biomedical and Biotechnology Research Journal
Subjects:
Online Access:http://www.bmbtrj.org/article.asp?issn=2588-9834;year=2019;volume=3;issue=1;spage=46;epage=52;aulast=Qi
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author Zheng Qi
Wei Yang
Yan-Fu Wang
Chang Liu
author_facet Zheng Qi
Wei Yang
Yan-Fu Wang
Chang Liu
author_sort Zheng Qi
collection DOAJ
description Background: This study analysis the epidemiological characteristics of incidence, gender, age, occupation, educational level, income, residence location, and timescale of 773 pulmonary tuberculosis patients in Hulin County in North China from 2014 to 2016. Methods: Two hundred and sixty-seven strains were identified and nine drug sensitivity tests against isoniazid (INH), streptomycin (S), ethambutol (EMB), rifampicin (RFP), ofloxacin (OFX), capreomycin, prothionamide, para-aminosalicylic acid (PAS), and kanamycin. Results: The top five drug resistance sequences of nine kinds of anti-TB drugs were S (24.535%) >INH (13.383%) >RFP (8.178%) >OFX (4.089%) >EMB (1.859%). Conclusion: The anti-TB medicine needs to be use under the guidelines to minimize drug resistance, and the elder age and poor also the work focus in the future.
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spelling doaj.art-04192074f0e24520b9016930d415f9582022-12-21T19:01:08ZengWolters Kluwer Medknow PublicationsBiomedical and Biotechnology Research Journal2588-98342588-98422019-01-0131465210.4103/bbrj.bbrj_141_18Pulmonary tuberculosis incidence and drug resistance-related factors analysis in North ChinaZheng QiWei YangYan-Fu WangChang LiuBackground: This study analysis the epidemiological characteristics of incidence, gender, age, occupation, educational level, income, residence location, and timescale of 773 pulmonary tuberculosis patients in Hulin County in North China from 2014 to 2016. Methods: Two hundred and sixty-seven strains were identified and nine drug sensitivity tests against isoniazid (INH), streptomycin (S), ethambutol (EMB), rifampicin (RFP), ofloxacin (OFX), capreomycin, prothionamide, para-aminosalicylic acid (PAS), and kanamycin. Results: The top five drug resistance sequences of nine kinds of anti-TB drugs were S (24.535%) >INH (13.383%) >RFP (8.178%) >OFX (4.089%) >EMB (1.859%). Conclusion: The anti-TB medicine needs to be use under the guidelines to minimize drug resistance, and the elder age and poor also the work focus in the future.http://www.bmbtrj.org/article.asp?issn=2588-9834;year=2019;volume=3;issue=1;spage=46;epage=52;aulast=QiFirst-line drugresistance ratesecond-line drugtuberculosis incidence
spellingShingle Zheng Qi
Wei Yang
Yan-Fu Wang
Chang Liu
Pulmonary tuberculosis incidence and drug resistance-related factors analysis in North China
Biomedical and Biotechnology Research Journal
First-line drug
resistance rate
second-line drug
tuberculosis incidence
title Pulmonary tuberculosis incidence and drug resistance-related factors analysis in North China
title_full Pulmonary tuberculosis incidence and drug resistance-related factors analysis in North China
title_fullStr Pulmonary tuberculosis incidence and drug resistance-related factors analysis in North China
title_full_unstemmed Pulmonary tuberculosis incidence and drug resistance-related factors analysis in North China
title_short Pulmonary tuberculosis incidence and drug resistance-related factors analysis in North China
title_sort pulmonary tuberculosis incidence and drug resistance related factors analysis in north china
topic First-line drug
resistance rate
second-line drug
tuberculosis incidence
url http://www.bmbtrj.org/article.asp?issn=2588-9834;year=2019;volume=3;issue=1;spage=46;epage=52;aulast=Qi
work_keys_str_mv AT zhengqi pulmonarytuberculosisincidenceanddrugresistancerelatedfactorsanalysisinnorthchina
AT weiyang pulmonarytuberculosisincidenceanddrugresistancerelatedfactorsanalysisinnorthchina
AT yanfuwang pulmonarytuberculosisincidenceanddrugresistancerelatedfactorsanalysisinnorthchina
AT changliu pulmonarytuberculosisincidenceanddrugresistancerelatedfactorsanalysisinnorthchina