The role of the gut microbiota in understanding functional gastrointestinal disorders
One of the most prevalent digestive diseases worldwide, functional gastrointestinal dysfunction (FGID) places a substantial strain on healthcare resources and causes significant morbidity. A study using Rome IV diagnostic criteria estimates the prevalence of FGID is about 40% worldwide. Most people...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Kazimierz Wielki University
2023-08-01
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| Series: | Journal of Education, Health and Sport |
| Subjects: | |
| Online Access: | https://apcz.umk.pl/JEHS/article/view/44762 |
| _version_ | 1797767503305244672 |
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| author | Witold Zardzewiały Radosław Bernacki Piotr Bernacki Oleksii Zaremskyi Martyna Dutka Dominik Szawica Aleksandra Kuźniar Michał Oleszko Edward Wąsiewicz |
| author_facet | Witold Zardzewiały Radosław Bernacki Piotr Bernacki Oleksii Zaremskyi Martyna Dutka Dominik Szawica Aleksandra Kuźniar Michał Oleszko Edward Wąsiewicz |
| author_sort | Witold Zardzewiały |
| collection | DOAJ |
| description |
One of the most prevalent digestive diseases worldwide, functional gastrointestinal dysfunction (FGID) places a substantial strain on healthcare resources and causes significant morbidity. A study using Rome IV diagnostic criteria estimates the prevalence of FGID is about 40% worldwide. Most people with FGID exhibit symptoms from the realm of psychopathology, most often anxiety and depression, making patients' quality of life lower compared to even those with chronic organic diseases. By elucidating the causes and consequences of qualitative and quantitative changes between the microbiota of a healthy person and the microbiota of a person with FDIG, incredible progress has been made in understanding the role of the gut microbiota in FGID. However, the exact cellular and molecular pathogens of FGID that are directed by the gut microbiota remain unknown, and learning more about them will result in non-empirical, but targeted therapies.
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| first_indexed | 2024-03-12T20:39:54Z |
| format | Article |
| id | doaj.art-0419879d272740f1949de97867c368ea |
| institution | Directory Open Access Journal |
| issn | 2391-8306 |
| language | English |
| last_indexed | 2024-03-12T20:39:54Z |
| publishDate | 2023-08-01 |
| publisher | Kazimierz Wielki University |
| record_format | Article |
| series | Journal of Education, Health and Sport |
| spelling | doaj.art-0419879d272740f1949de97867c368ea2023-08-01T10:47:41ZengKazimierz Wielki UniversityJournal of Education, Health and Sport2391-83062023-08-0130110.12775/JEHS.2023.30.01.009The role of the gut microbiota in understanding functional gastrointestinal disordersWitold Zardzewiały0Radosław Bernacki1Piotr Bernacki2Oleksii Zaremskyi3Martyna Dutka4Dominik Szawica5Aleksandra Kuźniar6Michał Oleszko7Edward Wąsiewicz8Uniwersytet Medyczny w Lublinie Aleje Racławickie 1, 20-059 Lublin Uniwersytet Medyczny w LublinieUniwersytet Medyczny w LublinieUniwersytet Medyczny w LublinieUniwersytet Medyczny w LublinieCENTRUM MEDYCZNE W ŁAŃCUCIE SP. Z O.O.Uniwersytet RzeszowskiUniwersytet RzeszowskiCENTRUM MEDYCZNE W ŁAŃCUCIE SP. Z O.O. One of the most prevalent digestive diseases worldwide, functional gastrointestinal dysfunction (FGID) places a substantial strain on healthcare resources and causes significant morbidity. A study using Rome IV diagnostic criteria estimates the prevalence of FGID is about 40% worldwide. Most people with FGID exhibit symptoms from the realm of psychopathology, most often anxiety and depression, making patients' quality of life lower compared to even those with chronic organic diseases. By elucidating the causes and consequences of qualitative and quantitative changes between the microbiota of a healthy person and the microbiota of a person with FDIG, incredible progress has been made in understanding the role of the gut microbiota in FGID. However, the exact cellular and molecular pathogens of FGID that are directed by the gut microbiota remain unknown, and learning more about them will result in non-empirical, but targeted therapies. https://apcz.umk.pl/JEHS/article/view/44762functional disordersirritable bowel syndromegastrointestinalfecal microbiota dysbiosis |
| spellingShingle | Witold Zardzewiały Radosław Bernacki Piotr Bernacki Oleksii Zaremskyi Martyna Dutka Dominik Szawica Aleksandra Kuźniar Michał Oleszko Edward Wąsiewicz The role of the gut microbiota in understanding functional gastrointestinal disorders Journal of Education, Health and Sport functional disorders irritable bowel syndrome gastrointestinal fecal microbiota dysbiosis |
| title | The role of the gut microbiota in understanding functional gastrointestinal disorders |
| title_full | The role of the gut microbiota in understanding functional gastrointestinal disorders |
| title_fullStr | The role of the gut microbiota in understanding functional gastrointestinal disorders |
| title_full_unstemmed | The role of the gut microbiota in understanding functional gastrointestinal disorders |
| title_short | The role of the gut microbiota in understanding functional gastrointestinal disorders |
| title_sort | role of the gut microbiota in understanding functional gastrointestinal disorders |
| topic | functional disorders irritable bowel syndrome gastrointestinal fecal microbiota dysbiosis |
| url | https://apcz.umk.pl/JEHS/article/view/44762 |
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