Secreted Osteoclastogenic Factor of Activated T Cells (SOFAT) Is Associated With Rheumatoid Arthritis and Joint Pain: Initial Evidences of a New Pathway

Secreted Osteoclastogenic Factor of Activated T Cells (SOFAT) Is Associated With Rheumatoid Arthritis and Joint Pain: Initial Evidences of a New Pathway

Rheumatoid arthritis (RA) has an inflammatory milieu in the synovial compartment, which is regulated by a complex cytokine and chemokine network that induces continuously degenerative and inflammatory reactions. The secreted osteoclastogenic factor of activated T cells (SOFAT) is a unique cytokine a...

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Bibliographic Details
Main Authors: Marcelo Henrique Napimoga, Weslley Danny Dantas Formiga, Henrique Ballassini Abdalla, Carlos Antônio Trindade-da-Silva, Camila Motta Venturin, Elizabeth Ferreira Martinez, Ana Carolina Rossaneis, Waldiceu A. Verri, Juliana Trindade Clemente-Napimoga
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Immunology
Subjects:
inflammation
SOFAT
rheumatoid arthritis
pain
osteoclast
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.01442/full

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