<i>N</i>-Benzo[<i>c</i>][1,2,5]thiazol-4-yl-3-trifluoromethylbenzamide

The title compound, <i>N</i>-benzo[<i>c</i>][1,2,5]thiazol-4-yl-3-trifluoromethylbenzamide (<b>1</b>) was synthesized by reacting 3-trifluoromethylbenzoyl chloride (<b>4</b>) and 4-aminobenzo[<i>c</i>][1,2,5]thiadiazole (<b>5</b>...

Full description

Bibliographic Details
Main Authors: Hamad H. Al Mamari, Nasser Al Awaimri, Yousuf Al Lawati
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:Molbank
Subjects:
Online Access:https://www.mdpi.com/1422-8599/2019/3/M1075
_version_ 1817988232446476288
author Hamad H. Al Mamari
Nasser Al Awaimri
Yousuf Al Lawati
author_facet Hamad H. Al Mamari
Nasser Al Awaimri
Yousuf Al Lawati
author_sort Hamad H. Al Mamari
collection DOAJ
description The title compound, <i>N</i>-benzo[<i>c</i>][1,2,5]thiazol-4-yl-3-trifluoromethylbenzamide (<b>1</b>) was synthesized by reacting 3-trifluoromethylbenzoyl chloride (<b>4</b>) and 4-aminobenzo[<i>c</i>][1,2,5]thiadiazole (<b>5</b>). The compound was characterized by various spectroscopic methods (<sup>1</sup>H NMR, <sup>13</sup>C NMR, IR, GC-MS) and its composition confirmed by elemental analysis. The importance of this compound lies in its possession of an <i>N</i>,<i>N</i>-bidentate directing group. Such a structural motif is potentially suitable for metal-catalyzed C-H bond functionalization reactions.
first_indexed 2024-04-14T00:32:44Z
format Article
id doaj.art-04205affbcf548b1adfff7bf0cf8af04
institution Directory Open Access Journal
issn 1422-8599
language English
last_indexed 2024-04-14T00:32:44Z
publishDate 2019-07-01
publisher MDPI AG
record_format Article
series Molbank
spelling doaj.art-04205affbcf548b1adfff7bf0cf8af042022-12-22T02:22:30ZengMDPI AGMolbank1422-85992019-07-0120193M107510.3390/M1075M1075<i>N</i>-Benzo[<i>c</i>][1,2,5]thiazol-4-yl-3-trifluoromethylbenzamideHamad H. Al Mamari0Nasser Al Awaimri1Yousuf Al Lawati2Department of Chemistry, College of Science, Sultan Qaboos University, PO Box 36, Al Khoudh, Muscat 123, OmanDepartment of Chemistry, College of Science, Sultan Qaboos University, PO Box 36, Al Khoudh, Muscat 123, OmanDepartment of Chemistry, College of Science, Sultan Qaboos University, PO Box 36, Al Khoudh, Muscat 123, OmanThe title compound, <i>N</i>-benzo[<i>c</i>][1,2,5]thiazol-4-yl-3-trifluoromethylbenzamide (<b>1</b>) was synthesized by reacting 3-trifluoromethylbenzoyl chloride (<b>4</b>) and 4-aminobenzo[<i>c</i>][1,2,5]thiadiazole (<b>5</b>). The compound was characterized by various spectroscopic methods (<sup>1</sup>H NMR, <sup>13</sup>C NMR, IR, GC-MS) and its composition confirmed by elemental analysis. The importance of this compound lies in its possession of an <i>N</i>,<i>N</i>-bidentate directing group. Such a structural motif is potentially suitable for metal-catalyzed C-H bond functionalization reactions.https://www.mdpi.com/1422-8599/2019/3/M1075benzamidebidentate directing groupC-H functionalization
spellingShingle Hamad H. Al Mamari
Nasser Al Awaimri
Yousuf Al Lawati
<i>N</i>-Benzo[<i>c</i>][1,2,5]thiazol-4-yl-3-trifluoromethylbenzamide
Molbank
benzamide
bidentate directing group
C-H functionalization
title <i>N</i>-Benzo[<i>c</i>][1,2,5]thiazol-4-yl-3-trifluoromethylbenzamide
title_full <i>N</i>-Benzo[<i>c</i>][1,2,5]thiazol-4-yl-3-trifluoromethylbenzamide
title_fullStr <i>N</i>-Benzo[<i>c</i>][1,2,5]thiazol-4-yl-3-trifluoromethylbenzamide
title_full_unstemmed <i>N</i>-Benzo[<i>c</i>][1,2,5]thiazol-4-yl-3-trifluoromethylbenzamide
title_short <i>N</i>-Benzo[<i>c</i>][1,2,5]thiazol-4-yl-3-trifluoromethylbenzamide
title_sort i n i benzo i c i 1 2 5 thiazol 4 yl 3 trifluoromethylbenzamide
topic benzamide
bidentate directing group
C-H functionalization
url https://www.mdpi.com/1422-8599/2019/3/M1075
work_keys_str_mv AT hamadhalmamari inibenzoici125thiazol4yl3trifluoromethylbenzamide
AT nasseralawaimri inibenzoici125thiazol4yl3trifluoromethylbenzamide
AT yousufallawati inibenzoici125thiazol4yl3trifluoromethylbenzamide