<i>N</i>-Benzo[<i>c</i>][1,2,5]thiazol-4-yl-3-trifluoromethylbenzamide
The title compound, <i>N</i>-benzo[<i>c</i>][1,2,5]thiazol-4-yl-3-trifluoromethylbenzamide (<b>1</b>) was synthesized by reacting 3-trifluoromethylbenzoyl chloride (<b>4</b>) and 4-aminobenzo[<i>c</i>][1,2,5]thiadiazole (<b>5</b>...
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MDPI AG
2019-07-01
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Online Access: | https://www.mdpi.com/1422-8599/2019/3/M1075 |
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author | Hamad H. Al Mamari Nasser Al Awaimri Yousuf Al Lawati |
author_facet | Hamad H. Al Mamari Nasser Al Awaimri Yousuf Al Lawati |
author_sort | Hamad H. Al Mamari |
collection | DOAJ |
description | The title compound, <i>N</i>-benzo[<i>c</i>][1,2,5]thiazol-4-yl-3-trifluoromethylbenzamide (<b>1</b>) was synthesized by reacting 3-trifluoromethylbenzoyl chloride (<b>4</b>) and 4-aminobenzo[<i>c</i>][1,2,5]thiadiazole (<b>5</b>). The compound was characterized by various spectroscopic methods (<sup>1</sup>H NMR, <sup>13</sup>C NMR, IR, GC-MS) and its composition confirmed by elemental analysis. The importance of this compound lies in its possession of an <i>N</i>,<i>N</i>-bidentate directing group. Such a structural motif is potentially suitable for metal-catalyzed C-H bond functionalization reactions. |
first_indexed | 2024-04-14T00:32:44Z |
format | Article |
id | doaj.art-04205affbcf548b1adfff7bf0cf8af04 |
institution | Directory Open Access Journal |
issn | 1422-8599 |
language | English |
last_indexed | 2024-04-14T00:32:44Z |
publishDate | 2019-07-01 |
publisher | MDPI AG |
record_format | Article |
series | Molbank |
spelling | doaj.art-04205affbcf548b1adfff7bf0cf8af042022-12-22T02:22:30ZengMDPI AGMolbank1422-85992019-07-0120193M107510.3390/M1075M1075<i>N</i>-Benzo[<i>c</i>][1,2,5]thiazol-4-yl-3-trifluoromethylbenzamideHamad H. Al Mamari0Nasser Al Awaimri1Yousuf Al Lawati2Department of Chemistry, College of Science, Sultan Qaboos University, PO Box 36, Al Khoudh, Muscat 123, OmanDepartment of Chemistry, College of Science, Sultan Qaboos University, PO Box 36, Al Khoudh, Muscat 123, OmanDepartment of Chemistry, College of Science, Sultan Qaboos University, PO Box 36, Al Khoudh, Muscat 123, OmanThe title compound, <i>N</i>-benzo[<i>c</i>][1,2,5]thiazol-4-yl-3-trifluoromethylbenzamide (<b>1</b>) was synthesized by reacting 3-trifluoromethylbenzoyl chloride (<b>4</b>) and 4-aminobenzo[<i>c</i>][1,2,5]thiadiazole (<b>5</b>). The compound was characterized by various spectroscopic methods (<sup>1</sup>H NMR, <sup>13</sup>C NMR, IR, GC-MS) and its composition confirmed by elemental analysis. The importance of this compound lies in its possession of an <i>N</i>,<i>N</i>-bidentate directing group. Such a structural motif is potentially suitable for metal-catalyzed C-H bond functionalization reactions.https://www.mdpi.com/1422-8599/2019/3/M1075benzamidebidentate directing groupC-H functionalization |
spellingShingle | Hamad H. Al Mamari Nasser Al Awaimri Yousuf Al Lawati <i>N</i>-Benzo[<i>c</i>][1,2,5]thiazol-4-yl-3-trifluoromethylbenzamide Molbank benzamide bidentate directing group C-H functionalization |
title | <i>N</i>-Benzo[<i>c</i>][1,2,5]thiazol-4-yl-3-trifluoromethylbenzamide |
title_full | <i>N</i>-Benzo[<i>c</i>][1,2,5]thiazol-4-yl-3-trifluoromethylbenzamide |
title_fullStr | <i>N</i>-Benzo[<i>c</i>][1,2,5]thiazol-4-yl-3-trifluoromethylbenzamide |
title_full_unstemmed | <i>N</i>-Benzo[<i>c</i>][1,2,5]thiazol-4-yl-3-trifluoromethylbenzamide |
title_short | <i>N</i>-Benzo[<i>c</i>][1,2,5]thiazol-4-yl-3-trifluoromethylbenzamide |
title_sort | i n i benzo i c i 1 2 5 thiazol 4 yl 3 trifluoromethylbenzamide |
topic | benzamide bidentate directing group C-H functionalization |
url | https://www.mdpi.com/1422-8599/2019/3/M1075 |
work_keys_str_mv | AT hamadhalmamari inibenzoici125thiazol4yl3trifluoromethylbenzamide AT nasseralawaimri inibenzoici125thiazol4yl3trifluoromethylbenzamide AT yousufallawati inibenzoici125thiazol4yl3trifluoromethylbenzamide |