Inter-Tumor Heterogeneity—Melanomas Respond Differently to GM-CSF-Mediated Activation

Inter-Tumor Heterogeneity—Melanomas Respond Differently to GM-CSF-Mediated Activation

Granulocyte-monocyte colony stimulating factor (GM-CSF) is used as an adjuvant in various clinical and preclinical studies with contradictory results. These were attributed to opposing effects of GM-CSF on the immune or myeloid systems of the treated patients or to lack of optimal dosing regimens. T...

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Bibliographic Details
Main Authors: Adi Moshe, Sivan Izraely, Orit Sagi-Assif, Sapir Malka, Shlomit Ben-Menachem, Tsipi Meshel, Metsada Pasmanik-Chor, Dave S.B. Hoon, Isaac P. Witz
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Cells
Subjects:
GM-CSF
melanoma
brain metastasis
metastatic microenvironment
Online Access:https://www.mdpi.com/2073-4409/9/7/1683

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