Validated Modernized Assay for Foscarnet in Pharmaceutical Formulations Using Suppressed Ion Chromatography Developed through a Quality by Design Approach

Validated Modernized Assay for Foscarnet in Pharmaceutical Formulations Using Suppressed Ion Chromatography Developed through a Quality by Design Approach

Inspired by the United States Pharmacopoeia (USP) “monograph modernization” initiative, we developed and validated an assay for foscarnet sodium injection solution (“foscavir”), following quality by design (QbD) principles, incorporating design of experiments (DoE) and multivariate data analysis to...

Full description

Bibliographic Details
Main Authors: Ngoc Phuoc Dinh, Adel Shamshir, Gjani Hulaj, Tobias Jonsson
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Separations
Subjects:
design of experiments
foscarnet
method development
monograph modernization
pharmaceutical quality control
suppressed ion chromatography
Online Access:https://www.mdpi.com/2297-8739/8/11/209

Similar Items

Similar Items