The nuclear egress complex of Epstein-Barr virus buds membranes through an oligomerization-driven mechanism.

During replication, herpesviral capsids are translocated from the nucleus into the cytoplasm by an unusual mechanism, termed nuclear egress, that involves capsid budding at the inner nuclear membrane. This process is mediated by the viral nuclear egress complex (NEC) that deforms the membrane around...

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Bibliographic Details
Main Authors: Michael K Thorsen, Elizabeth B Draganova, Ekaterina E Heldwein
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-07-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1010623

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