IL-17RA receptor signaling contributes to lung inflammation and parasite burden during Toxocara canis infection in mice

IL-17RA receptor signaling contributes to lung inflammation and parasite burden during Toxocara canis infection in mice

IL-17 is a cytokine produced by innate and acquired immunity cells that have an action against fungi and bacteria. However, its action in helminth infections is unclear, including in Toxocara canis infection. Toxocariasis is a neglected zoonosis representing a significant public health problem with...

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Bibliographic Details
Main Authors: Thaís Leal-Silva, Camila de Almeida Lopes, Flaviane Vieira-Santos, Fabrício Marcus Silva Oliveira, Lucas Kraemer, Luiza de Lima Silva Padrão, Chiara Cássia Oliveira Amorim, Jorge Lucas Nascimento Souza, Remo Castro Russo, Ricardo Toshio Fujiwara, Luisa Mourão Dias Magalhães, Lilian Lacerda Bueno
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Immunology
Subjects:
IL-17RA
toxocariasis
cytokines
helminth
inflammation
neutrophil
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.864632/full

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