Clinical Characteristics, Genetic Findings and Arrhythmic Outcomes of Patients with Catecholaminergic Polymorphic Ventricular Tachycardia from China: A Systematic Review

Clinical Characteristics, Genetic Findings and Arrhythmic Outcomes of Patients with Catecholaminergic Polymorphic Ventricular Tachycardia from China: A Systematic Review

Introduction: Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a rare inherited cardiac ion channelopathy. The present study aims to examine the clinical characteristics, genetic basis, and arrhythmic outcomes of CPVT patients from China to elucidate the difference between CPVT patien...

Full description

Bibliographic Details
Main Authors:	Justin Leung, Sharen Lee, Jiandong Zhou, Kamalan Jeevaratnam, Ishan Lakhani, Danny Radford, Emma Coakley-Youngs, Levent Pay, Göksel Çinier, Meltem Altinsoy, Amir Hossein Behnoush, Elham Mahmoudi, Paweł T. Matusik, George Bazoukis, Sebastian Garcia-Zamora, Shaoying Zeng, Ziliang Chen, Yunlong Xia, Tong Liu, Gary Tse
Format:	Article
Language:	English
Published:	MDPI AG 2022-07-01
Series:	Life
Subjects:	CPVT <i>RyR2</i> catecholaminergic polymorphic ventricular tachycardia
Online Access:	https://www.mdpi.com/2075-1729/12/8/1104

Similar Items

Flecainide Paradoxically Activates Cardiac Ryanodine Receptor Channels under Low Activity Conditions: A Potential Pro-Arrhythmic Action
by: Samantha C. Salvage, et al.
Published: (2021-08-01)

An Optogenetic Arrhythmia Model—Insertion of Several Catecholaminergic Polymorphic Ventricular Tachycardia Mutations Into Caenorhabditis elegans UNC-68 Disturbs Calstabin-Mediated Stabilization of the Ryanodine Receptor Homolog
by: Marcial Alexander Engel, et al.
Published: (2022-03-01)

Therapeutic Approaches of Ryanodine Receptor-Associated Heart Diseases
by: Norbert Szentandrássy, et al.
Published: (2022-04-01)

Description of a novel RyR2 mutation in a juvenile patient with symptomatic catecholaminergic polymorphic ventricular tachycardia in sleep and during exercise: a case report
by: L. K. Seidlmayer, et al.
Published: (2018-10-01)

Generation of two induced pluripotent stem cell lines from catecholaminergic polymorphic ventricular tachycardia patients carrying RYR2 mutations
by: Xiaohui Kong, et al.
Published: (2023-06-01)

CPVT and Complete Atrio-Ventricular Block: The Flipside of the Same Coin
by: Mattia Petrungaro, et al.
Published: (2023-02-01)

Efficacy of Flecainide in Catecholaminergic Polymorphic Ventricular Tachycardia Is Mutation-Independent but Reduced by Calcium Overload
by: Hyun Seok Hwang, et al.
Published: (2019-08-01)

Diagnosis of catecholaminergic polymorphic ventricular tachycardia during late adulthood due to a rare genetic variant in RYR2: a case report
by: Laura García-Cano, et al.
Published: (2021-08-01)

Whole-exome sequencing in familial type 2 diabetes identifies an atypical missense variant in the RyR2 gene
by: Vikas Bansal, et al.
Published: (2024-02-01)

Clinical Characteristics, Genetic Basis and Healthcare Resource Utilisation and Costs in Patients with Catecholaminergic Polymorphic Ventricular Tachycardia: A Retrospective Cohort Study
by: Cheuk To Chung, et al.
Published: (2022-08-01)

Catecholaminergic polymorphic ventricular tachycardia: An exciting new era
by: Shashank P Behere, et al.
Published: (2016-01-01)

Cardiac arrest in a mother and daughter and the identification of a novel RYR2 variant, predisposing to low penetrant catecholaminergic polymorphic ventricular tachycardia in a four‐generation Canadian family
by: Matthew Tung, et al.
Published: (2020-04-01)

Flipping syncope: The case of an adolescent athlete with syncopal episodes ultimately diagnosed with catecholaminergic polymorphic ventricular tachycardia
by: Collin C. Kramer, et al.
Published: (2020-08-01)

Defective ryanodine receptor N-terminus inter-subunit interaction is a common mechanism in neuromuscular and cardiac disorders
by: Yadan Zhang, et al.
Published: (2022-10-01)

A Type 2 Ryanodine Receptor Variant in the Helical Domain 2 Associated with an Impairment of the Adrenergic Response
by: Malorie Blancard, et al.
Published: (2021-06-01)

A Recurrent Exertional Syncope and Sudden Cardiac Arrest in a Young Athlete with Known Pathogenic p.Arg420Gln Variant in the <em>RYR2</em> Gene
by: Małgorzata Stępień-Wojno, et al.
Published: (2020-06-01)

Modeling Catecholaminergic Polymorphic Ventricular Tachycardia using Induced Pluripotent Stem Cell-derived Cardiomyocytes
by: Atara Novak, et al.
Published: (2012-07-01)

Ryanodine receptor 2 promotes colorectal cancer metastasis by the ROS/BACH1 axis
by: Tianwei Chen, et al.
Published: (2023-04-01)

Characterization of the mechanism by which a nonsense variant in RYR2 leads to disordered calcium handling
by: Claire Hopton, et al.
Published: (2022-04-01)

The RyR2-R2474S Mutation Sensitizes Cardiomyocytes and Hearts to Catecholaminergic Stress-Induced Oxidation of the Mitochondrial Glutathione Pool
by: Jörg W. Wegener, et al.
Published: (2021-12-01)

Maternal exercise preserves offspring cardiovascular health via oxidative regulation of the ryanodine receptorWhat is known?What new information does this article contribute?Novelty and significance:
by: Kelsey M. Pinckard, et al.
Published: (2024-04-01)

Identification of RyR2-PBmice and the effects of transposon insertional mutagenesis of the RyR2 gene on cardiac function in mice
by: Qianqian Wang, et al.
Published: (2019-05-01)

Specific association of growth-associated protein 43 with calcium release units in skeletal muscles of lower vertebrates
by: G.A. Caprara, et al.
Published: (2014-10-01)

Arrhythmia-Associated Calmodulin E105A Mutation Alters the Binding Affinity of CaM to a Ryanodine Receptor 2 CaM-Binding Pocket
by: Angelos Thanassoulas, et al.
Published: (2023-10-01)

Modality specific roles for metabotropic GABAergic signaling and calcium induced calcium release mechanisms in regulating cold nociception
by: Atit A. Patel, et al.
Published: (2022-09-01)

Extraction and determination of flubendiamide insecticide in food samples: A review
by: S. Aghris, et al.
Published: (2022-01-01)

Finite element model to study calcium distribution in oocytes involving voltage gated Ca2+ channel, ryanodine receptor and buffers
by: Parvaiz Ahmad Naik, et al.
Published: (2016-03-01)

The Arianna thread: the matching of S-100 family with the RyR’s muscle receptor
by: Giorgio Fano Illic, et al.
Published: (2020-03-01)

Arrhythmogenic Mechanism of Catecholaminergic Polymorphic Ventricular Tachycardia
by: Nian Liu, MD, et al.
Published: (2006-01-01)

Genetic Inhibition of Mitochondrial Permeability Transition Pore Exacerbates Ryanodine Receptor 2 Dysfunction in Arrhythmic Disease
by: Arpita Deb, et al.
Published: (2023-01-01)

Direct regulation of the cardiac ryanodine receptor (RyR2) by O-GlcNAcylation
by: Chidinma A Okolo, et al.
Published: (2023-10-01)

Fushenmu treatment ameliorates RyR2 with related metabolites in a zebrafish model of barium chloride induced arrhythmia
by: Yan-Ting Zhao, et al.
Published: (2023-08-01)

R-carvedilol, a potential new therapy for Alzheimer’s disease
by: Jinjing Yao, et al.
Published: (2022-11-01)

Corrigendum: R-carvedilol, a potential new therapy for Alzheimer’s disease
by: Jinjing Yao, et al.
Published: (2023-01-01)

Endoplasmic Reticulum-Based Calcium Dysfunctions in Synucleinopathies
by: Gergo Kovacs, et al.
Published: (2021-10-01)

6-minute walk test as a measure of disease progression and fatigability in a cohort of individuals with RYR1-related myopathies
by: Jessica W. Witherspoon, et al.
Published: (2018-07-01)

Catecholaminergic polymorphic ventricular tachycardia in 2012
by: Christian van der Werf, et al.
Published: (2011-12-01)

Advances in the Molecular Genetics of Catecholaminergic Polymorphic Ventricular Tachycardia
by: Junxia Song, et al.
Published: (2021-08-01)

Local Control Model of a Human Ventricular Myocyte: An Exploration of Frequency-Dependent Changes and Calcium Sparks
by: Jerome Anthony E. Alvarez, et al.
Published: (2023-08-01)

Discordant Calcium Transient and Action Potential Alternans in a Canine Left-Ventricular Myocyte
by: Armoundas, Antonis A.
Published: (2010)