Organocatalytic Synthesis of γ-Amino Acid Precursors via Masked Acetaldehyde under Micellar Catalysis
The development of micellar catalysis offers a sustainable alternative to organic solvents, and represents an environmental milestone in organic synthesis. Here, the first Michael addition of masked acetaldehyde under neutral, cationic and anionic micellar catalysis is reported, affording the produc...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Georg Thieme Verlag KG
2023-01-01
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| Series: | SynOpen |
| Subjects: | |
| Online Access: | http://www.thieme-connect.de/DOI/DOI?10.1055/a-1996-8940 |
| _version_ | 1797938786752004096 |
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| author | Maria Edith Casacchia Giuliana Giorgianni Elena Allegritti Luisa Giansanti Armando Carlone Fabio Pesciaioli |
| author_facet | Maria Edith Casacchia Giuliana Giorgianni Elena Allegritti Luisa Giansanti Armando Carlone Fabio Pesciaioli |
| author_sort | Maria Edith Casacchia |
| collection | DOAJ |
| description | The development of micellar catalysis offers a sustainable alternative to organic solvents, and represents an environmental milestone in organic synthesis. Here, the first Michael addition of masked acetaldehyde under neutral, cationic and anionic micellar catalysis is reported, affording the products in high yields and enantiomeric excess, despite the use of water as solvent. |
| first_indexed | 2024-04-10T19:06:16Z |
| format | Article |
| id | doaj.art-0429bd57400546d5933b3b7da4acd3ee |
| institution | Directory Open Access Journal |
| issn | 2509-9396 |
| language | English |
| last_indexed | 2024-04-10T19:06:16Z |
| publishDate | 2023-01-01 |
| publisher | Georg Thieme Verlag KG |
| record_format | Article |
| series | SynOpen |
| spelling | doaj.art-0429bd57400546d5933b3b7da4acd3ee2023-01-31T00:21:24ZengGeorg Thieme Verlag KGSynOpen2509-93962023-01-010701293210.1055/a-1996-8940Organocatalytic Synthesis of γ-Amino Acid Precursors via Masked Acetaldehyde under Micellar CatalysisMaria Edith Casacchia0Giuliana Giorgianni1Elena Allegritti2Luisa Giansanti3Armando Carlone4Fabio Pesciaioli5Dipartimento di Scienze Fisiche e Chimiche, Università degli Studi dell’AquilaDipartimento di Scienze Fisiche e Chimiche, Università degli Studi dell’AquilaDipartimento di Scienze Fisiche e Chimiche, Università degli Studi dell’AquilaDipartimento di Scienze Fisiche e Chimiche, Università degli Studi dell’AquilaDipartimento di Scienze Fisiche e Chimiche, Università degli Studi dell’AquilaDipartimento di Scienze Fisiche e Chimiche, Università degli Studi dell’AquilaThe development of micellar catalysis offers a sustainable alternative to organic solvents, and represents an environmental milestone in organic synthesis. Here, the first Michael addition of masked acetaldehyde under neutral, cationic and anionic micellar catalysis is reported, affording the products in high yields and enantiomeric excess, despite the use of water as solvent.http://www.thieme-connect.de/DOI/DOI?10.1055/a-1996-8940micellar catalysisaminocatalysisasymmetric synthesisγ-amino acidsgreen chemistry |
| spellingShingle | Maria Edith Casacchia Giuliana Giorgianni Elena Allegritti Luisa Giansanti Armando Carlone Fabio Pesciaioli Organocatalytic Synthesis of γ-Amino Acid Precursors via Masked Acetaldehyde under Micellar Catalysis SynOpen micellar catalysis aminocatalysis asymmetric synthesis γ-amino acids green chemistry |
| title | Organocatalytic Synthesis of γ-Amino Acid Precursors via Masked Acetaldehyde under Micellar Catalysis |
| title_full | Organocatalytic Synthesis of γ-Amino Acid Precursors via Masked Acetaldehyde under Micellar Catalysis |
| title_fullStr | Organocatalytic Synthesis of γ-Amino Acid Precursors via Masked Acetaldehyde under Micellar Catalysis |
| title_full_unstemmed | Organocatalytic Synthesis of γ-Amino Acid Precursors via Masked Acetaldehyde under Micellar Catalysis |
| title_short | Organocatalytic Synthesis of γ-Amino Acid Precursors via Masked Acetaldehyde under Micellar Catalysis |
| title_sort | organocatalytic synthesis of γ amino acid precursors via masked acetaldehyde under micellar catalysis |
| topic | micellar catalysis aminocatalysis asymmetric synthesis γ-amino acids green chemistry |
| url | http://www.thieme-connect.de/DOI/DOI?10.1055/a-1996-8940 |
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