Effects of Clinical and Laboratory Findings on Prognosis of Patients with Acute Pancreatitis: Retrospective Evaluation

Purpose: Acute pancreatitis(AP) is a disease that seen with abdominal pain and high serum amylase and lipase levels. Its mortality and morbidity are high. In this study, the demographic data, clinical and laboratory findings of patients hospitalized in our hospital with a diagnosis of AP were anal...

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Main Authors: İhsan SOLMAZ, Songül ARAÇ, Nazım EKİN, Burhan Sami KALIN
Format: Article
Language:English
Published: Kirsehir Ahi Evran University 2021-08-01
Series:Ahi Evran Medical Journal
Subjects:
Online Access:https://dergipark.org.tr/tr/download/article-file/1275534
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author İhsan SOLMAZ
Songül ARAÇ
Nazım EKİN
Burhan Sami KALIN
author_facet İhsan SOLMAZ
Songül ARAÇ
Nazım EKİN
Burhan Sami KALIN
author_sort İhsan SOLMAZ
collection DOAJ
description Purpose: Acute pancreatitis(AP) is a disease that seen with abdominal pain and high serum amylase and lipase levels. Its mortality and morbidity are high. In this study, the demographic data, clinical and laboratory findings of patients hospitalized in our hospital with a diagnosis of AP were analyzed, and the effects of these findings on prognosis were investigated retrospectively. Materials and Methods: This study was conducted on 457 patients who were followed up with the AP diagnosis at our hospital's Internal Medicine and Emergency Medicine Clinic between January 2016 and January 2019. Results: Of the patients, 160 (35%) were male, 297 were female (65%), and the mean age was 57.7 (min:18-max:106). All of our patients who died were over 70 years old and had at least one comorbidity. There was no statistically significant difference between mild and severe AP patients in terms of gender, etiology, CRP, amylase, and hospitalization days. There was a strong significance in terms of age. The etiology of 369 (80.7%) of our patients originated from the gall bladder, and causes of 88 (19.3%) of them were not related to the gallbladder. The average Ranson score of the patients was 1.28. Conclusion: Considering that the severity of the disease increases significantly with age, we think that it is important to monitor elderly patients carefully and to be followed up in centers with intensive care units. Because of the different clinical characteristics of patients with AP, determining the clinical severity in the early period can provide an effective treatment approach and minimize the complications that may develop.
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spelling doaj.art-042edaed6d7345ccbd574b0e7a0ebd362023-02-15T16:16:18ZengKirsehir Ahi Evran UniversityAhi Evran Medical Journal2619-92032021-08-01528589https://doi.org/10.46332/aemj.790888Effects of Clinical and Laboratory Findings on Prognosis of Patients with Acute Pancreatitis: Retrospective Evaluationİhsan SOLMAZ0https://orcid.org/0000-0002-6624-8063Songül ARAÇ1https://orcid.org/0000-0001-6830-3639Nazım EKİN2https://orcid.org/0000-0001-5302-8953Burhan Sami KALIN3https://orcid.org/0000-0003-2624-6175SAĞLIK BİLİMLERİ ÜNİVERSİTESİ, DİYARBAKIR GAZİ YAŞARGİL SAĞLIK UYGULAMA VE ARAŞTIRMA MERKEZİ, DAHİLİ TIP BİLİMLERİ BÖLÜMÜSAĞLIK BİLİMLERİ ÜNİVERSİTESİ, DİYARBAKIR GAZİ YAŞARGİL SAĞLIK UYGULAMA VE ARAŞTIRMA MERKEZİ, CERRAHİ TIP BİLİMLERİ BÖLÜMÜ, İLK VE ACİL YARDIM ANABİLİM DALISAĞLIK BİLİMLERİ ÜNİVERSİTESİ, DİYARBAKIR GAZİ YAŞARGİL SAĞLIK UYGULAMA VE ARAŞTIRMA MERKEZİ, DAHİLİ TIP BİLİMLERİ BÖLÜMÜSAĞLIK BİLİMLERİ ÜNİVERSİTESİ, DİYARBAKIR GAZİ YAŞARGİL SAĞLIK UYGULAMA VE ARAŞTIRMA MERKEZİ, DAHİLİ TIP BİLİMLERİ BÖLÜMÜPurpose: Acute pancreatitis(AP) is a disease that seen with abdominal pain and high serum amylase and lipase levels. Its mortality and morbidity are high. In this study, the demographic data, clinical and laboratory findings of patients hospitalized in our hospital with a diagnosis of AP were analyzed, and the effects of these findings on prognosis were investigated retrospectively. Materials and Methods: This study was conducted on 457 patients who were followed up with the AP diagnosis at our hospital's Internal Medicine and Emergency Medicine Clinic between January 2016 and January 2019. Results: Of the patients, 160 (35%) were male, 297 were female (65%), and the mean age was 57.7 (min:18-max:106). All of our patients who died were over 70 years old and had at least one comorbidity. There was no statistically significant difference between mild and severe AP patients in terms of gender, etiology, CRP, amylase, and hospitalization days. There was a strong significance in terms of age. The etiology of 369 (80.7%) of our patients originated from the gall bladder, and causes of 88 (19.3%) of them were not related to the gallbladder. The average Ranson score of the patients was 1.28. Conclusion: Considering that the severity of the disease increases significantly with age, we think that it is important to monitor elderly patients carefully and to be followed up in centers with intensive care units. Because of the different clinical characteristics of patients with AP, determining the clinical severity in the early period can provide an effective treatment approach and minimize the complications that may develop.https://dergipark.org.tr/tr/download/article-file/1275534epidemiologyetiologypancreatitis severityranson
spellingShingle İhsan SOLMAZ
Songül ARAÇ
Nazım EKİN
Burhan Sami KALIN
Effects of Clinical and Laboratory Findings on Prognosis of Patients with Acute Pancreatitis: Retrospective Evaluation
Ahi Evran Medical Journal
epidemiology
etiology
pancreatitis severity
ranson
title Effects of Clinical and Laboratory Findings on Prognosis of Patients with Acute Pancreatitis: Retrospective Evaluation
title_full Effects of Clinical and Laboratory Findings on Prognosis of Patients with Acute Pancreatitis: Retrospective Evaluation
title_fullStr Effects of Clinical and Laboratory Findings on Prognosis of Patients with Acute Pancreatitis: Retrospective Evaluation
title_full_unstemmed Effects of Clinical and Laboratory Findings on Prognosis of Patients with Acute Pancreatitis: Retrospective Evaluation
title_short Effects of Clinical and Laboratory Findings on Prognosis of Patients with Acute Pancreatitis: Retrospective Evaluation
title_sort effects of clinical and laboratory findings on prognosis of patients with acute pancreatitis retrospective evaluation
topic epidemiology
etiology
pancreatitis severity
ranson
url https://dergipark.org.tr/tr/download/article-file/1275534
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AT songularac effectsofclinicalandlaboratoryfindingsonprognosisofpatientswithacutepancreatitisretrospectiveevaluation
AT nazımekin effectsofclinicalandlaboratoryfindingsonprognosisofpatientswithacutepancreatitisretrospectiveevaluation
AT burhansamikalin effectsofclinicalandlaboratoryfindingsonprognosisofpatientswithacutepancreatitisretrospectiveevaluation