Evaluation of single domain antibodies as nuclear tracers for imaging of the immune checkpoint receptor human lymphocyte activation gene-3 in cancer

Evaluation of single domain antibodies as nuclear tracers for imaging of the immune checkpoint receptor human lymphocyte activation gene-3 in cancer

Abstract Recent advancements in the field of immune-oncology have led to a significant increase in life expectancy of patients with diverse forms of cancer, such as hematologic malignancies, melanoma and lung cancer. Unfortunately, these encouraging results are not observed in the majority of patien...

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Bibliographic Details
Main Authors: Q. Lecocq, P. Debie, J. Puttemans, R. M. Awad, L. De Beck, T. Ertveldt, Y. De Vlaeminck, C. Goyvaerts, G. Raes, M. Keyaerts, K. Breckpot, N. Devoogdt
Format: Article
Language:English
Published: SpringerOpen 2021-11-01
Series:EJNMMI Research
Subjects:
Immunotherapy
Immune checkpoint
Lymphocyte activation gene-3
Single-domain antibody
Nanobody
Molecular imaging
Online Access:https://doi.org/10.1186/s13550-021-00857-9

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