Chinese and Global Burdens of Gastrointestinal Cancers From 1990 to 2019
BackgroundGastrointestinal (GI) cancers are an important component of the tumor. This study aimed to investigate the burden of six major GI cancers in China and globally from 1990 to 2019.MethodsWe conducted a cross-sectional study based on the Global Burden of Disease Study (GBD) 2019. Indicators o...
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Frontiers Media S.A.
2022-07-01
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| Series: | Frontiers in Public Health |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fpubh.2022.941284/full |
| _version_ | 1811292333006651392 |
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| author | Wangcheng Xie Tingsong Yang Jieliang Zuo Zhilong Ma Weidi Yu Zhengyu Hu Zhenshun Song Zhenshun Song |
| author_facet | Wangcheng Xie Tingsong Yang Jieliang Zuo Zhilong Ma Weidi Yu Zhengyu Hu Zhenshun Song Zhenshun Song |
| author_sort | Wangcheng Xie |
| collection | DOAJ |
| description | BackgroundGastrointestinal (GI) cancers are an important component of the tumor. This study aimed to investigate the burden of six major GI cancers in China and globally from 1990 to 2019.MethodsWe conducted a cross-sectional study based on the Global Burden of Disease Study (GBD) 2019. Indicators on incidence, deaths, disability-adjusted life-years (DALYs), and risk factors for esophageal, stomach, liver, pancreatic, colon and rectum, and gallbladder and biliary tract cancers were collected and analyzed for time trends. The contribution of each cancer and the proportion of cases in China among global cases were further reported.ResultsGlobal incidence cases, death cases, and DALYs of GI cancers showed an overall ascending trend over the past 30 years, but there was temporal and geographical variation across cancer types. By 2019, colon and rectum cancer had overtaken stomach cancer as the most burdensome GI cancer globally. However, stomach cancer narrowly continued to be the most burdensome GI in China. In addition, the proportion of incidence and death cases of stomach, pancreatic, colon and rectum, and gallbladder and biliary tract cancers among global cases had further increased. It was noteworthy that the burden of liver cancer in China has been alleviated significantly.ConclusionGI cancers remain a major public health problem in China and globally. Despite the temporal and geographic diversity of different cancers, targeted primary and secondary prevention are still necessary for the future to face these unknown challenges. |
| first_indexed | 2024-04-13T04:44:47Z |
| format | Article |
| id | doaj.art-043ae12b2a034da59c26ea59423dfc25 |
| institution | Directory Open Access Journal |
| issn | 2296-2565 |
| language | English |
| last_indexed | 2024-04-13T04:44:47Z |
| publishDate | 2022-07-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Public Health |
| spelling | doaj.art-043ae12b2a034da59c26ea59423dfc252022-12-22T03:01:53ZengFrontiers Media S.A.Frontiers in Public Health2296-25652022-07-011010.3389/fpubh.2022.941284941284Chinese and Global Burdens of Gastrointestinal Cancers From 1990 to 2019Wangcheng Xie0Tingsong Yang1Jieliang Zuo2Zhilong Ma3Weidi Yu4Zhengyu Hu5Zhenshun Song6Zhenshun Song7Department of General Surgery, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, ChinaDepartment of General Surgery, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, ChinaDepartment of General Surgery, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, ChinaDepartment of General Surgery, Tongren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, ChinaDepartment of General Surgery, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, ChinaDepartment of General Surgery, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, ChinaDepartment of General Surgery, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, ChinaDepartment of General Surgery, Shanghai Fourth People's Hospital, Tongji University School of Medicine, Shanghai, ChinaBackgroundGastrointestinal (GI) cancers are an important component of the tumor. This study aimed to investigate the burden of six major GI cancers in China and globally from 1990 to 2019.MethodsWe conducted a cross-sectional study based on the Global Burden of Disease Study (GBD) 2019. Indicators on incidence, deaths, disability-adjusted life-years (DALYs), and risk factors for esophageal, stomach, liver, pancreatic, colon and rectum, and gallbladder and biliary tract cancers were collected and analyzed for time trends. The contribution of each cancer and the proportion of cases in China among global cases were further reported.ResultsGlobal incidence cases, death cases, and DALYs of GI cancers showed an overall ascending trend over the past 30 years, but there was temporal and geographical variation across cancer types. By 2019, colon and rectum cancer had overtaken stomach cancer as the most burdensome GI cancer globally. However, stomach cancer narrowly continued to be the most burdensome GI in China. In addition, the proportion of incidence and death cases of stomach, pancreatic, colon and rectum, and gallbladder and biliary tract cancers among global cases had further increased. It was noteworthy that the burden of liver cancer in China has been alleviated significantly.ConclusionGI cancers remain a major public health problem in China and globally. Despite the temporal and geographic diversity of different cancers, targeted primary and secondary prevention are still necessary for the future to face these unknown challenges.https://www.frontiersin.org/articles/10.3389/fpubh.2022.941284/fulldeathdisability-adjusted life-yearsgastrointestinal cancerincidencerisk factor |
| spellingShingle | Wangcheng Xie Tingsong Yang Jieliang Zuo Zhilong Ma Weidi Yu Zhengyu Hu Zhenshun Song Zhenshun Song Chinese and Global Burdens of Gastrointestinal Cancers From 1990 to 2019 Frontiers in Public Health death disability-adjusted life-years gastrointestinal cancer incidence risk factor |
| title | Chinese and Global Burdens of Gastrointestinal Cancers From 1990 to 2019 |
| title_full | Chinese and Global Burdens of Gastrointestinal Cancers From 1990 to 2019 |
| title_fullStr | Chinese and Global Burdens of Gastrointestinal Cancers From 1990 to 2019 |
| title_full_unstemmed | Chinese and Global Burdens of Gastrointestinal Cancers From 1990 to 2019 |
| title_short | Chinese and Global Burdens of Gastrointestinal Cancers From 1990 to 2019 |
| title_sort | chinese and global burdens of gastrointestinal cancers from 1990 to 2019 |
| topic | death disability-adjusted life-years gastrointestinal cancer incidence risk factor |
| url | https://www.frontiersin.org/articles/10.3389/fpubh.2022.941284/full |
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