Formation of ibrutinib solvates: so similar, yet so different

Formation of ibrutinib solvates: so similar, yet so different

The transformation processes of non-solvated ibrutinib into a series of halogenated benzene solvates are explored in detail here. The transformation was studied in real time by X-ray powder diffraction in a glass capillary. Crystal structures of chlorobenzene, bromobenzene and iodobenzene solvates a...

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Bibliographic Details
Main Authors:	Jan Jirát, Jan Rohlíček, Jakub Kaminský, Tomáš Jirkal, Luděk Ridvan, Eliška Skořepová, Vít Zvoníček, Michal Dušek, Miroslav Šoóš
Format:	Article
Language:	English
Published:	International Union of Crystallography 2023-03-01
Series:	IUCrJ
Subjects:	ibrutinib multicomponent crystal solvates transformation mechanisms
Online Access:	http://scripts.iucr.org/cgi-bin/paper?S2052252523001197

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