Lathyrol promotes ER stress-induced apoptosis and proliferation inhibition in lung cancer cells by targeting SERCA2

Lathyrol promotes ER stress-induced apoptosis and proliferation inhibition in lung cancer cells by targeting SERCA2

Lathyrol is a natural product isolated from the traditional Chinese medicine Semen Euphorbiae with unknown anti-tumor effects. We found that lathyrol had significant inhibitory effect on lung cancer cells by inducing apoptosis and inhibiting proliferation. Subsequently, we demonstrated for the first...

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Bibliographic Details
Main Authors: Peng Chen, Yiqian Li, Zhou Zhou, Chuqi Pan, Linghui Zeng
Format: Article
Language:English
Published: Elsevier 2023-02-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Lathyrol
ER stress
Lung cancer
SERCA2
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332222015128

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