The role of antenatal corticosteroids in twin pregnancy
Twin pregnancy was associated with significantly higher rates of adverse neonatal and perinatal outcomes. One of the underlying causes is that twins are prone to preterm birth. Antenatal corticosteroids are widely used for reducing the incidence of neonatal respiratory distress syndrome initially an...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-02-01
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| Series: | Frontiers in Pharmacology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fphar.2023.1072578/full |
| _version_ | 1797936144960192512 |
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| author | Jie Zhu Jie Zhu Shuyue Li Shuyue Li Ying Zhao Ying Zhao Yu Xiong Yu Xiong |
| author_facet | Jie Zhu Jie Zhu Shuyue Li Shuyue Li Ying Zhao Ying Zhao Yu Xiong Yu Xiong |
| author_sort | Jie Zhu |
| collection | DOAJ |
| description | Twin pregnancy was associated with significantly higher rates of adverse neonatal and perinatal outcomes. One of the underlying causes is that twins are prone to preterm birth. Antenatal corticosteroids are widely used for reducing the incidence of neonatal respiratory distress syndrome initially and other neonatal mortality and morbidities subsequently. As it is widely used as a prophylactic treatment for potential premature births, there remain controversies of issues relating to twin gestations, including window for opportunity, timing of use, repeat course, optimal administration-to-delivery intervals, dosage, and type of corticosteroid. Thus, we present a thorough review of antenatal corticosteroids usage in twin gestation, emphasizing the aforementioned issues and attempting to offer direction for future investigation and clinical practice. |
| first_indexed | 2024-04-10T18:26:13Z |
| format | Article |
| id | doaj.art-044231f8cfd74510943fc15f2357b8e9 |
| institution | Directory Open Access Journal |
| issn | 1663-9812 |
| language | English |
| last_indexed | 2024-04-10T18:26:13Z |
| publishDate | 2023-02-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Pharmacology |
| spelling | doaj.art-044231f8cfd74510943fc15f2357b8e92023-02-02T05:40:48ZengFrontiers Media S.A.Frontiers in Pharmacology1663-98122023-02-011410.3389/fphar.2023.10725781072578The role of antenatal corticosteroids in twin pregnancyJie Zhu0Jie Zhu1Shuyue Li2Shuyue Li3Ying Zhao4Ying Zhao5Yu Xiong6Yu Xiong7Obstetrics and Gynecology Hospital, Fudan University, Shanghai, ChinaThe Shanghai Key Laboratory of Female Reproductive Endocrine-Related Diseases, Shanghai, ChinaObstetrics and Gynecology Hospital, Fudan University, Shanghai, ChinaThe Shanghai Key Laboratory of Female Reproductive Endocrine-Related Diseases, Shanghai, ChinaObstetrics and Gynecology Hospital, Fudan University, Shanghai, ChinaThe Shanghai Key Laboratory of Female Reproductive Endocrine-Related Diseases, Shanghai, ChinaObstetrics and Gynecology Hospital, Fudan University, Shanghai, ChinaThe Shanghai Key Laboratory of Female Reproductive Endocrine-Related Diseases, Shanghai, ChinaTwin pregnancy was associated with significantly higher rates of adverse neonatal and perinatal outcomes. One of the underlying causes is that twins are prone to preterm birth. Antenatal corticosteroids are widely used for reducing the incidence of neonatal respiratory distress syndrome initially and other neonatal mortality and morbidities subsequently. As it is widely used as a prophylactic treatment for potential premature births, there remain controversies of issues relating to twin gestations, including window for opportunity, timing of use, repeat course, optimal administration-to-delivery intervals, dosage, and type of corticosteroid. Thus, we present a thorough review of antenatal corticosteroids usage in twin gestation, emphasizing the aforementioned issues and attempting to offer direction for future investigation and clinical practice.https://www.frontiersin.org/articles/10.3389/fphar.2023.1072578/fullantenatal corticosteroidstwin pregnanciesrespiratory distress syndromecorticosteroidspreterm birth |
| spellingShingle | Jie Zhu Jie Zhu Shuyue Li Shuyue Li Ying Zhao Ying Zhao Yu Xiong Yu Xiong The role of antenatal corticosteroids in twin pregnancy Frontiers in Pharmacology antenatal corticosteroids twin pregnancies respiratory distress syndrome corticosteroids preterm birth |
| title | The role of antenatal corticosteroids in twin pregnancy |
| title_full | The role of antenatal corticosteroids in twin pregnancy |
| title_fullStr | The role of antenatal corticosteroids in twin pregnancy |
| title_full_unstemmed | The role of antenatal corticosteroids in twin pregnancy |
| title_short | The role of antenatal corticosteroids in twin pregnancy |
| title_sort | role of antenatal corticosteroids in twin pregnancy |
| topic | antenatal corticosteroids twin pregnancies respiratory distress syndrome corticosteroids preterm birth |
| url | https://www.frontiersin.org/articles/10.3389/fphar.2023.1072578/full |
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