A scoring model for predicting prognosis of patients with severe fever with thrombocytopenia syndrome.

Severe fever with thrombocytopenia syndrome (SFTS) is an emerging epidemic infectious disease caused by the SFTS bunyavirus (SFTSV) with an estimated high case-fatality rate of 12.7% to 32.6%. Currently, the disease has been reported in mainland China, Japan, Korea, and the United States. At present...

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Main Authors: Bei Jia, Xiaomin Yan, Yuxin Chen, Guiyang Wang, Yong Liu, Biyun Xu, Peixin Song, Yang Li, Yali Xiong, Weihua Wu, Yingying Hao, Juan Xia, Zhaoping Zhang, Rui Huang, Chao Wu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-09-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC5626493?pdf=render
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author Bei Jia
Xiaomin Yan
Yuxin Chen
Guiyang Wang
Yong Liu
Biyun Xu
Peixin Song
Yang Li
Yali Xiong
Weihua Wu
Yingying Hao
Juan Xia
Zhaoping Zhang
Rui Huang
Chao Wu
author_facet Bei Jia
Xiaomin Yan
Yuxin Chen
Guiyang Wang
Yong Liu
Biyun Xu
Peixin Song
Yang Li
Yali Xiong
Weihua Wu
Yingying Hao
Juan Xia
Zhaoping Zhang
Rui Huang
Chao Wu
author_sort Bei Jia
collection DOAJ
description Severe fever with thrombocytopenia syndrome (SFTS) is an emerging epidemic infectious disease caused by the SFTS bunyavirus (SFTSV) with an estimated high case-fatality rate of 12.7% to 32.6%. Currently, the disease has been reported in mainland China, Japan, Korea, and the United States. At present, there is no specific antiviral therapy for SFTSV infection. Considering the higher mortality rate and rapid clinical progress of SFTS, supporting the appropriate treatment in time to SFTS patients is critical. Therefore, it is very important for clinicians to predict these SFTS cases who are more likely to have a poor prognosis or even more likely to decease. In the present study, we established a simple and feasible model for assessing the severity and predicting the prognosis of SFTS patients with high sensitivity and specificity. This model may aid the physicians to immediately initiate prompt treatment to block the rapid development of the illness and reduce the fatality of SFTS patients.
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spelling doaj.art-0444bef05c364c6faac0beffcf9afbdc2022-12-22T02:06:37ZengPublic Library of Science (PLoS)PLoS Neglected Tropical Diseases1935-27271935-27352017-09-01119e000590910.1371/journal.pntd.0005909A scoring model for predicting prognosis of patients with severe fever with thrombocytopenia syndrome.Bei JiaXiaomin YanYuxin ChenGuiyang WangYong LiuBiyun XuPeixin SongYang LiYali XiongWeihua WuYingying HaoJuan XiaZhaoping ZhangRui HuangChao WuSevere fever with thrombocytopenia syndrome (SFTS) is an emerging epidemic infectious disease caused by the SFTS bunyavirus (SFTSV) with an estimated high case-fatality rate of 12.7% to 32.6%. Currently, the disease has been reported in mainland China, Japan, Korea, and the United States. At present, there is no specific antiviral therapy for SFTSV infection. Considering the higher mortality rate and rapid clinical progress of SFTS, supporting the appropriate treatment in time to SFTS patients is critical. Therefore, it is very important for clinicians to predict these SFTS cases who are more likely to have a poor prognosis or even more likely to decease. In the present study, we established a simple and feasible model for assessing the severity and predicting the prognosis of SFTS patients with high sensitivity and specificity. This model may aid the physicians to immediately initiate prompt treatment to block the rapid development of the illness and reduce the fatality of SFTS patients.http://europepmc.org/articles/PMC5626493?pdf=render
spellingShingle Bei Jia
Xiaomin Yan
Yuxin Chen
Guiyang Wang
Yong Liu
Biyun Xu
Peixin Song
Yang Li
Yali Xiong
Weihua Wu
Yingying Hao
Juan Xia
Zhaoping Zhang
Rui Huang
Chao Wu
A scoring model for predicting prognosis of patients with severe fever with thrombocytopenia syndrome.
PLoS Neglected Tropical Diseases
title A scoring model for predicting prognosis of patients with severe fever with thrombocytopenia syndrome.
title_full A scoring model for predicting prognosis of patients with severe fever with thrombocytopenia syndrome.
title_fullStr A scoring model for predicting prognosis of patients with severe fever with thrombocytopenia syndrome.
title_full_unstemmed A scoring model for predicting prognosis of patients with severe fever with thrombocytopenia syndrome.
title_short A scoring model for predicting prognosis of patients with severe fever with thrombocytopenia syndrome.
title_sort scoring model for predicting prognosis of patients with severe fever with thrombocytopenia syndrome
url http://europepmc.org/articles/PMC5626493?pdf=render
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