A pilot meta-analysis on self-reported efficacy of neurofeedback for adolescents and adults with ADHD
Abstract Self-reported effectiveness of electroencephalogram-based neurofeedback (EEG-NF) against the core symptoms of attention-deficit hyperactivity disorder (ADHD) in adolescents/adults remains unclear. We searched PubMed, Embase, ClinicalKey, Cochrane CENTRAL, ScienceDirect, Web of Science, and...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2022-06-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-022-14220-y |
| _version_ | 1811242184873082880 |
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| author | Hsin-Yi Fan Cheuk-Kwan Sun Yu-Shian Cheng Weilun Chung Ruu‐Fen Tzang Hsien‐Jane Chiu Chun-Ning Ho Kuo-Chuan Hung |
| author_facet | Hsin-Yi Fan Cheuk-Kwan Sun Yu-Shian Cheng Weilun Chung Ruu‐Fen Tzang Hsien‐Jane Chiu Chun-Ning Ho Kuo-Chuan Hung |
| author_sort | Hsin-Yi Fan |
| collection | DOAJ |
| description | Abstract Self-reported effectiveness of electroencephalogram-based neurofeedback (EEG-NF) against the core symptoms of attention-deficit hyperactivity disorder (ADHD) in adolescents/adults remains unclear. We searched PubMed, Embase, ClinicalKey, Cochrane CENTRAL, ScienceDirect, Web of Science, and ClinicalTrials.gov from inception to August 2021 for randomized clinical trials (RCTs) of EEG-NF with self-reported ADHD symptom ratings. Comparators included participants on waitlist/treatment as usual (TAU) or receiving other interventions. Of the 279 participants (mean age = 23.48; range: 6–60) in five eligible RCTs, 183 received EEG-NF treatment. Forest plot demonstrated no difference in inattention (SMD = −0.11, 95% CI −0.39–0.18, p = 0.46), total score (SMD = −0.08, 95% CI −0.36–0.2, p = 0.56), and hyperactivity/impulsivity (SMD = 0.01, 95% CI −0.23–0.25, p = 0.91) between EEG-NF and comparison groups. Nevertheless, compared with waitlist/TAU, EEG-NF showed better improvement in inattention (SMD = −0.48, 95% CI −0.9–−0.06, p = 0.03) but not hyperactivity/impulsivity (SMD = −0.03, 95% CI −0.45–0.38, p = 0.87). Follow-up 6–12 months demonstrated no difference in inattention (SMD = −0.01, 95% CI −0.41–0.38, p = 0.94), total score (SMD = 0.22, 95% CI −0.08–0.52, p = 0.15), and hyperactivity/impulsivity (SMD = −0.01, 95% CI −0.27–0.26, p = 0.96) between the two groups. Dropout rate also showed no difference (RR = 1.05, 95% CI 0.82–1.33, p = 0.72). Our results support EEG-NF for improving inattention in adolescents/young adults, although its effectiveness against hyperactivity/impulsivity remains inconclusive. |
| first_indexed | 2024-04-12T13:48:05Z |
| format | Article |
| id | doaj.art-0448214771aa487db2639cd8fd2b9f46 |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-04-12T13:48:05Z |
| publishDate | 2022-06-01 |
| publisher | Nature Portfolio |
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| series | Scientific Reports |
| spelling | doaj.art-0448214771aa487db2639cd8fd2b9f462022-12-22T03:30:37ZengNature PortfolioScientific Reports2045-23222022-06-0112111010.1038/s41598-022-14220-yA pilot meta-analysis on self-reported efficacy of neurofeedback for adolescents and adults with ADHDHsin-Yi Fan0Cheuk-Kwan Sun1Yu-Shian Cheng2Weilun Chung3Ruu‐Fen Tzang4Hsien‐Jane Chiu5Chun-Ning Ho6Kuo-Chuan Hung7Department of Psychiatry, Tsyr-Huey Mental HospitalDepartment of Emergency Medicine, E-Da HospitalDepartment of Psychiatry, Tsyr-Huey Mental HospitalDepartment of Psychiatry, Tsyr-Huey Mental HospitalDepartment of Psychiatry, Mackay Memorial HospitalTaoyuan Psychiatric Center, Ministry of Health and WelfareDepartment of Anesthesiology, Chi Mei Medical CenterDepartment of Anesthesiology, Chi Mei Medical CenterAbstract Self-reported effectiveness of electroencephalogram-based neurofeedback (EEG-NF) against the core symptoms of attention-deficit hyperactivity disorder (ADHD) in adolescents/adults remains unclear. We searched PubMed, Embase, ClinicalKey, Cochrane CENTRAL, ScienceDirect, Web of Science, and ClinicalTrials.gov from inception to August 2021 for randomized clinical trials (RCTs) of EEG-NF with self-reported ADHD symptom ratings. Comparators included participants on waitlist/treatment as usual (TAU) or receiving other interventions. Of the 279 participants (mean age = 23.48; range: 6–60) in five eligible RCTs, 183 received EEG-NF treatment. Forest plot demonstrated no difference in inattention (SMD = −0.11, 95% CI −0.39–0.18, p = 0.46), total score (SMD = −0.08, 95% CI −0.36–0.2, p = 0.56), and hyperactivity/impulsivity (SMD = 0.01, 95% CI −0.23–0.25, p = 0.91) between EEG-NF and comparison groups. Nevertheless, compared with waitlist/TAU, EEG-NF showed better improvement in inattention (SMD = −0.48, 95% CI −0.9–−0.06, p = 0.03) but not hyperactivity/impulsivity (SMD = −0.03, 95% CI −0.45–0.38, p = 0.87). Follow-up 6–12 months demonstrated no difference in inattention (SMD = −0.01, 95% CI −0.41–0.38, p = 0.94), total score (SMD = 0.22, 95% CI −0.08–0.52, p = 0.15), and hyperactivity/impulsivity (SMD = −0.01, 95% CI −0.27–0.26, p = 0.96) between the two groups. Dropout rate also showed no difference (RR = 1.05, 95% CI 0.82–1.33, p = 0.72). Our results support EEG-NF for improving inattention in adolescents/young adults, although its effectiveness against hyperactivity/impulsivity remains inconclusive.https://doi.org/10.1038/s41598-022-14220-y |
| spellingShingle | Hsin-Yi Fan Cheuk-Kwan Sun Yu-Shian Cheng Weilun Chung Ruu‐Fen Tzang Hsien‐Jane Chiu Chun-Ning Ho Kuo-Chuan Hung A pilot meta-analysis on self-reported efficacy of neurofeedback for adolescents and adults with ADHD Scientific Reports |
| title | A pilot meta-analysis on self-reported efficacy of neurofeedback for adolescents and adults with ADHD |
| title_full | A pilot meta-analysis on self-reported efficacy of neurofeedback for adolescents and adults with ADHD |
| title_fullStr | A pilot meta-analysis on self-reported efficacy of neurofeedback for adolescents and adults with ADHD |
| title_full_unstemmed | A pilot meta-analysis on self-reported efficacy of neurofeedback for adolescents and adults with ADHD |
| title_short | A pilot meta-analysis on self-reported efficacy of neurofeedback for adolescents and adults with ADHD |
| title_sort | pilot meta analysis on self reported efficacy of neurofeedback for adolescents and adults with adhd |
| url | https://doi.org/10.1038/s41598-022-14220-y |
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