Serotonin: beyond menopause
Serotonin is a brain neurotransmitter, a local gut-produced pro-kinetic agent and a platelets-released monoamine with haemostasis role. We focus on revealing the serotonin interferences with menopause mainly related to climacteric syndrome and bone health. This is a short commentary type of manuscri...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Amaltea Medical Publishing House
2016-09-01
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| Series: | Romanian Journal of Medical Practice |
| Subjects: | |
| Online Access: | https://rjmp.com.ro/articles/2016.3/RJMP_2016_3_Art-10.pdf |
| _version_ | 1819110072681234432 |
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| author | Mara Carsote Eugenia Nedeltcheva Petrova Otilia Radu Andrei Goldstein Adina Ghemigian Ana Valea |
| author_facet | Mara Carsote Eugenia Nedeltcheva Petrova Otilia Radu Andrei Goldstein Adina Ghemigian Ana Valea |
| author_sort | Mara Carsote |
| collection | DOAJ |
| description | Serotonin is a brain neurotransmitter, a local gut-produced pro-kinetic agent and a platelets-released monoamine with haemostasis role. We focus on revealing the serotonin interferences with menopause mainly related to climacteric syndrome and bone health. This is a short commentary type of manuscript, centred on English language PubMed research. Serotonin is connected to the hypothalamic thresholds for temperature regulation in vasomotor symptoms that is why drugs that elevate the serotonin synaptic plaque exposure like SSRI (serotonin selective reuptake inhibitors) are indicated. Serotonin is also linked to bone field but its testing into the blood has not been unanimously found to be correlated with bone mineral density
or menopausal bone remodelling markers. Conditions with age-related onset as carcinoid tumours bring a serotonin excess but not necessary a bone loss. From climacteric syndrome to bone regulation and to pathological domain of neuroendocrine neoplasia, serotonin plays a complex role on menopause’s field. |
| first_indexed | 2024-12-22T03:35:55Z |
| format | Article |
| id | doaj.art-044d860584204ae7ad9cbfdf3997e9ce |
| institution | Directory Open Access Journal |
| issn | 1842-8258 2069-6108 |
| language | English |
| last_indexed | 2024-12-22T03:35:55Z |
| publishDate | 2016-09-01 |
| publisher | Amaltea Medical Publishing House |
| record_format | Article |
| series | Romanian Journal of Medical Practice |
| spelling | doaj.art-044d860584204ae7ad9cbfdf3997e9ce2022-12-21T18:40:22ZengAmaltea Medical Publishing HouseRomanian Journal of Medical Practice1842-82582069-61082016-09-0111326827010.37897/RJMP.2016.3.10Serotonin: beyond menopauseMara Carsote0Eugenia Nedeltcheva Petrova1Otilia Radu2Andrei Goldstein3Adina Ghemigian4Ana Valea5“Carol Davila” University of Medicine and Pharmacy, Bucharest; “C.I. Parhon” National Institute of Endocrinology, Bucharest“C.I. Parhon” National Institute of Endocrinology, Bucharest“Carol Davila” University of Medicine and Pharmacy, Bucharest“C.I. Parhon” National Institute of Endocrinology, Bucharest“Carol Davila” University of Medicine and Pharmacy, Bucharest; “C.I. Parhon” National Institute of Endocrinology, Bucharest“Iuliu Hatieganu” University of Medicine and Pharmacy, Clinical County Hospital, Cluj-NapocaSerotonin is a brain neurotransmitter, a local gut-produced pro-kinetic agent and a platelets-released monoamine with haemostasis role. We focus on revealing the serotonin interferences with menopause mainly related to climacteric syndrome and bone health. This is a short commentary type of manuscript, centred on English language PubMed research. Serotonin is connected to the hypothalamic thresholds for temperature regulation in vasomotor symptoms that is why drugs that elevate the serotonin synaptic plaque exposure like SSRI (serotonin selective reuptake inhibitors) are indicated. Serotonin is also linked to bone field but its testing into the blood has not been unanimously found to be correlated with bone mineral density or menopausal bone remodelling markers. Conditions with age-related onset as carcinoid tumours bring a serotonin excess but not necessary a bone loss. From climacteric syndrome to bone regulation and to pathological domain of neuroendocrine neoplasia, serotonin plays a complex role on menopause’s field.https://rjmp.com.ro/articles/2016.3/RJMP_2016_3_Art-10.pdfserotoninboneclimacteric syndrome |
| spellingShingle | Mara Carsote Eugenia Nedeltcheva Petrova Otilia Radu Andrei Goldstein Adina Ghemigian Ana Valea Serotonin: beyond menopause Romanian Journal of Medical Practice serotonin bone climacteric syndrome |
| title | Serotonin: beyond menopause |
| title_full | Serotonin: beyond menopause |
| title_fullStr | Serotonin: beyond menopause |
| title_full_unstemmed | Serotonin: beyond menopause |
| title_short | Serotonin: beyond menopause |
| title_sort | serotonin beyond menopause |
| topic | serotonin bone climacteric syndrome |
| url | https://rjmp.com.ro/articles/2016.3/RJMP_2016_3_Art-10.pdf |
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